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© Marion Coolen
Radial glia neural stem cells of the adult zebrafish telencephalon electroporated with a membrane tagged GFP
Publication : PloS one

Inter-individual and inter-strain variations in zebrafish locomotor ontogeny

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in PloS one - 09 Aug 2013

Lange M, Neuzeret F, Fabreges B, Froc C, Bedu S, Bally-Cuif L, Norton WH

Link to Pubmed [PMID] – 23950910

PLoS ONE 2013;8(8):e70172

Zebrafish exhibit remarkable alterations in behaviour and morphology as they develop from early larval stages to mature adults. In this study we compare the locomotion parameters of six common zebrafish strains from two different laboratories to determine the stability and repeatability of these behaviours. Our results demonstrate large variability in locomotion and fast swim events between strains and between laboratories across time. These data highlight the necessity for careful, strain-specific controls when analysing locomotor phenotypes and open up the possibility of standardising the quantification of zebrafish behaviour at multiple life stages.

http://www.ncbi.nlm.nih.gov/pubmed/23950910