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© Research
Publication : Transplantation

Human myoblast engraftment is improved in laminin-enriched microenvironment

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Transplantation - 27 Feb 2008

Silva-Barbosa SD, Butler-Browne GS, de Mello W, Riederer I, Di Santo JP, Savino W, Mouly V

Link to Pubmed [PMID] – 18347536

Transplantation 2008 Feb;85(4):566-75

One major challenge in developing cell therapy for muscle diseases is to define the best condition for the recipient’s muscle to niche donor cells. We have examined the efficiency of human myoblast transplantation in an immunodeficient animal model, after local irradiation, as well as the potential impact of laminin on myoblast behavior.

http://www.ncbi.nlm.nih.gov/pubmed/18347536