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© Therese Couderc, Marc Lecuit
Publication : Microbes and infection / Institut Pasteur

Human listeriosis and animal models

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Microbes and infection / Institut Pasteur - 22 May 2007

Lecuit M

Link to Pubmed [PMID] – 17720601

Microbes Infect. 2007 Aug;9(10):1216-25

Human listeriosis is a potentially fatal foodborne infection caused by Listeria monocytogenes, an opportunistic psychrophile bacterium that is widespread in the environment. It has only recently emerged as a significant cause of human infection in industrialized countries, owing to appearance of a vulnerable population of immunocompromised individuals, and the concomitant development of large-scale agro-industrial plants and refrigerated food. Here we review the main clinical features of human listeriosis and highlight specificities and similarities with animal listeriosis in diverse species. Finally, we present some of the critical determinants for the choice of an appropriate animal model to study human listeriosis.

http://www.ncbi.nlm.nih.gov/pubmed/17720601