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© Pierre Gounon
Entrée de Listeria dans une cellule épithéliale (Grossissement X 10000). Image colorisée.
Publication : Future microbiology

How the study of Listeria monocytogenes has led to new concepts in biology

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Future microbiology - 12 Jun 2017

Rolhion N, Cossart P

Link to Pubmed [PMID] – 28604108

Future Microbiol 2017 06;12:621-638

The opportunistic intracellular bacterial pathogen Listeria monocytogenes has in 30 years emerged as an exceptional bacterial model system in infection biology. Research on this bacterium has provided considerable insight into how pathogenic bacteria adapt to mammalian hosts, invade eukaryotic cells, move intracellularly, interfere with host cell functions and disseminate within tissues. It also contributed to unveil features of normal host cell pathways and unsuspected functions of previously known cellular proteins. This review provides an updated overview of our knowledge on this pathogen. In many examples, findings on L. monocytogenes provided the basis for new concepts in bacterial regulation, cell biology and infection processes.

https://www.ncbi.nlm.nih.gov/pubmed/28604108