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Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
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Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Operations
Head of Structure
Honorary President of the Departement
Labex Coordinator

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An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity

Rifampin-moxifloxacin-metronidazole combination therapy for severe Hurley Stage 1 Hidradenitis Suppurativa: prospective short-term trial and one-year follow-up in 28 consecutive patients.

Mosquitoes were orally infected with the chikungunya virus. Midguts were dissected at day 5 post-infection, fixed and permeabilised. Virus is shown in red (anti-E2 protein, cyanine 3), the actin network in green (phalloidin 548) and nuclei in blue (DAPI).

Publication : Parasites & vectors

Gene copy number and function of the APL1 immune factor changed during Anopheles evolution

Team: Genetics and Genomics of Insect Vectors

Member: Christian Mitri

Scientific Fields

Diseases

Organisms

Applications

Technique

Published in Parasites & vectors - 13 Jan 2020

Mitri C, Bischoff E, Eiglmeier K, Holm I, Dieme C, Brito-Fravallo E, Raz A, Zakeri S, Nejad MIK, Djadid ND, Vernick KD, Riehle MM

Link to Pubmed [PMID] – 31931885

Parasit Vectors 2020 Jan;13(1):18

The recent reference genome assembly and annotation of the Asian malaria vector Anopheles stephensi detected only one gene encoding the leucine-rich repeat immune factor APL1, while in the Anopheles gambiae and sibling Anopheles coluzzii, APL1 factors are encoded by a family of three paralogs. The phylogeny and biological function of the unique APL1 gene in An. stephensi have not yet been specifically examined.

https://www.ncbi.nlm.nih.gov/pubmed/31931885

Published on: 13 Jan 2020