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© Institut Pasteur
Cryptococcus neoformans
Publication : Frontiers in cellular and infection microbiology

Extracellular Vesicles in Fungi: Past, Present, and Future Perspectives.

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Frontiers in cellular and infection microbiology - 01 Jan 2020

Rizzo J, Rodrigues ML, Janbon G,

Link to Pubmed [PMID] – 32760680

Link to DOI [DOI] – 10.3389/fcimb.2020.00346

Front Cell Infect Microbiol 2020 ; 10(): 346

Extracellular vesicles (EVs) have garnered much interest in the cell biology and biomedical research fields. Many studies have reported the existence of EVs in all types of living cells, including in fifteen different fungal genera. EVs play diverse biological roles, from the regulation of physiological events and response to specific environmental conditions to the mediation of highly complex interkingdom communications. This review will provide a historical perspective on EVs produced by fungi and an overview of the recent discoveries in the field. We will also review the current knowledge about EV biogenesis and cargo, their role in cell-to-cell interactions, and methods of EV analysis. Finally, we will discuss the perspectives of EVs as vehicles for the delivery of biologically active molecules.

https://pubmed.ncbi.nlm.nih.gov/32760680