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© Research
Publication : Cancer epidemiology, biomarkers & prevention

Circulating mitochondrial DNA level, a noninvasive biomarker for the early detection of gastric cancer

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Cancer epidemiology, biomarkers & prevention - 26 Aug 2014

Fernandes J, Michel V, Camorlinga-Ponce M, Gomez A, Maldonado C, De Reuse H, Torres J, Touati E

Link to Pubmed [PMID] – 25159292

Cancer Epidemiol. Biomarkers Prev. 2014 Nov;23(11):2430-8

Gastric cancer represents a major health burden worldwide and is often diagnosed at an advanced stage. Biomarkers for screening and prevention of gastric cancer are missing. Changes in peripheral blood mitochondrial DNA (mtDNA) have emerged as a potential preventive/diagnosis biomarker for cancer risk. We aimed to determine whether peripheral leukocytes mtDNA levels are associated with stages of the gastric carcinogenesis cascade.

http://www.ncbi.nlm.nih.gov/pubmed/25159292