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© Research
Publication : Emerging infectious diseases

Candida spp. with acquired echinocandin resistance, France, 2004-2010.

Member: Françoise Dromer
Member: Marie Desnos-Ollivier
Member: Stéphane Bretagne
Member: Dea Garcia-Hermoso
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Emerging infectious diseases - 01 Jan 2012

Dannaoui E, Desnos-Ollivier M, Garcia-Hermoso D, Grenouillet F, Cassaing S, Baixench MT, Bretagne S, Dromer F, Lortholary O, ,

Link to Pubmed [PMID] – 22257484

Link to DOI – 10.3201/eid1801.110556

Emerg Infect Dis 2012 Jan; 18(1): 86-90

We report 20 episodes of infection caused by acquired echinocandin-resistant Candida spp. harboring diverse and new Fksp mutations. For 12 patients, initial isolates (low MIC, wild-type Fksp sequence) and subsequent isolates (after caspofungin treatment, high MIC, mutated Fksp) were genetically related.