Link to Pubmed [PMID] – 22257484
Emerging Infect. Dis. 2012 Jan;18(1):86-90
We report 20 episodes of infection caused by acquired echinocandin-resistant Candida spp. harboring diverse and new Fksp mutations. For 12 patients, initial isolates (low MIC, wild-type Fksp sequence) and subsequent isolates (after caspofungin treatment, high MIC, mutated Fksp) were genetically related.
http://www.ncbi.nlm.nih.gov/pubmed/22257484