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© Pierre Gounon
Entrée de Listeria dans une cellule épithéliale (Grossissement X 10000). Image colorisée.
Publication : Future microbiology

Bacterial and cellular RNAs at work during Listeria infection

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Future microbiology - 01 Jan 2014

Sesto N, Koutero M, Cossart P

Link to Pubmed [PMID] – 25340833

Future Microbiol 2014;9(9):1025-37

Listeria monocytogenes is an intracellular pathogen that can enter and invade host cells. In the course of its infection, RNA-mediated regulatory mechanisms provide a fast and versatile response for both the bacterium and the host. They regulate a variety of processes, such as environment sensing and virulence in pathogenic bacteria, as well as development, cellular differentiation, metabolism and immune responses in eukaryotic cells. The aim of this article is to summarize first the RNA-mediated regulatory mechanisms that play a role in the Listeria lifestyle and in its virulence, and then the host miRNA responses to Listeria infection. Finally, we discuss the potential cross-talk between bacterial RNAs and host RNA regulatory mechanisms as new mechanisms of bacterial virulence.

http://www.ncbi.nlm.nih.gov/pubmed/25340833