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© A-M. Pais-Correia, M-I. Thoulouze, A. Alcover, A. Gessain
Mise en évidence de structures de type "biofilm ", formées par le rétrovirus HTLV-1 générés par des cellules infectées (cellules du haut), qui ont été transmis à un autre lymphocyte (cellule du bas). Micrographie en microscopie électronique à balayage. Image colorisée.
Publication : Journal of colloid and interface science

Antimicrobial peptide encapsulation and sustained release from polymer network particles prepared in supercritical carbon dioxide.

Team: Oncogenic Virus Epidemiology and Pathophysiology
Team: Virus and Immunity
Member: Isma Ziani
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of colloid and interface science - 15 Dec 2018

Parilti R, Caprasse J, Riva R, Alexandre M, Vandegaart H, Bebrone C, Dupont-Gillain C, Howdle SM, Jérôme C,

Link to Pubmed [PMID] – 30077061

Link to DOI – 10.1016/j.jcis.2018.07.125S0021-9797(18)30890-7

J Colloid Interface Sci 2018 Dec; 532(): 112-117

Antimicrobial peptide loaded poly(2-hydroxyethyl methacrylate) particles were synthesized in supercritical carbon dioxide via one-pot free-radical dispersion polymerisation of 2-hydroxyethyl methacrylate and a cross-linker. Discrete particles with a well-defined spherical morphology and a diameter as low as 450 nm have been obtained in mild conditions. The encapsulation and release of the peptide were confirmed by antimicrobial tests that demonstrated for the first time a sustained release of the peptide from poly(2-hydroxyethyl methacrylate) microgels prepared by one-pot dispersion polymerization in supercritical carbon dioxide and then dispersed in water.