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© A-M. Pais-Correia, M-I. Thoulouze, A. Alcover, A. Gessain
Mise en évidence de structures de type "biofilm ", formées par le rétrovirus HTLV-1 générés par des cellules infectées (cellules du haut), qui ont été transmis à un autre lymphocyte (cellule du bas). Micrographie en microscopie électronique à balayage. Image colorisée.
Publication : Journal of colloid and interface science

Antimicrobial peptide encapsulation and sustained release from polymer network particles prepared in supercritical carbon dioxide.

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of colloid and interface science - 15 Dec 2018

Parilti R, Caprasse J, Riva R, Alexandre M, Vandegaart H, Bebrone C, Dupont-Gillain C, Howdle SM, Jérôme C,

Link to Pubmed [PMID] – 30077061

Link to DOI – 10.1016/j.jcis.2018.07.125S0021-9797(18)30890-7

J Colloid Interface Sci 2018 Dec; 532(): 112-117

Antimicrobial peptide loaded poly(2-hydroxyethyl methacrylate) particles were synthesized in supercritical carbon dioxide via one-pot free-radical dispersion polymerisation of 2-hydroxyethyl methacrylate and a cross-linker. Discrete particles with a well-defined spherical morphology and a diameter as low as 450 nm have been obtained in mild conditions. The encapsulation and release of the peptide were confirmed by antimicrobial tests that demonstrated for the first time a sustained release of the peptide from poly(2-hydroxyethyl methacrylate) microgels prepared by one-pot dispersion polymerization in supercritical carbon dioxide and then dispersed in water.