Link to Pubmed [PMID] – 33976238
Link to DOI – 996710.1038/s41598-021-88945-7
Sci Rep 2021 May; 11(1): 9967
Genes encoding synaptic proteins are highly associated with neuronal disorders many of which show clinical co-morbidity. We integrated 58 published synaptic proteomic datasets that describe over 8000 proteins and combined them with direct protein-protein interactions and functional metadata to build a network resource that reveals the shared and unique protein components that underpin multiple disorders. All the data are provided in a flexible and accessible format to encourage custom use.