• 2014
  Wain-Hobson S, An avian H7N1 gain-of-function experiment of great concern, MBio 2014;5(5):e01882-14.
• 2014
  Caval V, Suspène R, Shapira M, Vartanian JP, Wain-Hobson S, A prevalent cancer susceptibility APOBEC3A hybrid allele bearing APOBEC3B 3’UTR enhances chromosomal DNA damage, Nat Commun 2014;5:5129.
• 2014
  Kostrzak A, Henry M, Demoyen PL, Wain-Hobson S, Vartanian JP, APOBEC3A catabolism of electroporated plasmid DNA in mouse muscle, Gene Ther. 2015 Jan;22(1):96-103.
• 2014
  Wain-Hobson S, The Irrationality of GOF Avian Influenza Virus Research, Front Public Health 2014;2:77.
• 2014
  Suspène R, Caval V, Henry M, Bouzidi MS, Wain-Hobson S, Vartanian JP, Erroneous identification of APOBEC3-edited chromosomal DNA in cancer genomics, Br. J. Cancer 2014 May;110(10):2615-22.
• 2013
  Caval V, Suspène R, Vartanian JP, Wain-Hobson S, Orthologous mammalian APOBEC3A cytidine deaminases hypermutate nuclear DNA, Mol. Biol. Evol. 2014 Feb;31(2):330-40.
• 2013
  Wain-Hobson S, Pandemic influenza viruses: time to recognize our inability to predict the unpredictable and stop dangerous gain-of-function experiments, EMBO Mol Med 2013 Nov;5(11):1637-41.
• 2013
  Rey F, Schwartz O, Wain-Hobson S, Gain-of-function research: unknown risks, Science 2013 Oct;342(6156):311.
• 2013
  Mussil B, Suspène R, Aynaud MM, Gauvrit A, Vartanian JP, Wain-Hobson S, Human APOBEC3A isoforms translocate to the nucleus and induce DNA double strand breaks leading to cell stress and death, PLoS ONE 2013;8(8):e73641.
• 2013
  Suspène R, Aynaud MM, Vartanian JP, Wain-Hobson S, Efficient deamination of 5-methylcytidine and 5-substituted cytidine residues in DNA by human APOBEC3A cytidine deaminase, PLoS ONE 2013;8(6):e63461.
• 2013
  Wain-Hobson S, H5N1 viral-engineering dangers will not go away, Nature 2013 Mar;495(7442):411.
• 2012
  Ezzikouri S, Kitab B, Rebbani K, Marchio A, Wain-Hobson S, Dejean A, Vartanian JP, Pineau P, Benjelloun S, Polymorphic APOBEC3 modulates chronic hepatitis B in Moroccan population, J. Viral Hepat. 2013 Oct;20(10):678-86.
• 2012
  Dosset M, Godet Y, Vauchy C, Beziaud L, Lone YC, Sedlik C, Liard C, Levionnois E, Clerc B, Sandoval F, Daguindau E, Wain-Hobson S, Tartour E, Langlade-Demoyen P, Borg C, Adotévi O, Universal cancer peptide-based therapeutic vaccine breaks tolerance against telomerase and eradicates established tumor, Clin. Cancer Res. 2012 Nov;18(22):6284-95.
• 2012
  Ko NL, Birlouez E, Wain-Hobson S, Mahieux R, Vartanian JP, Hyperediting of human T-cell leukemia virus type 2 and simian T-cell leukemia virus type 3 by the dsRNA adenosine deaminase ADAR-1, J. Gen. Virol. 2012 Dec;93(Pt 12):2646-51.
• 2012
  Aynaud MM, Suspène R, Vidalain PO, Mussil B, Guétard D, Tangy F, Wain-Hobson S, Vartanian JP, Human Tribbles 3 protects nuclear DNA from cytidine deamination by APOBEC3A, J. Biol. Chem. 2012 Nov;287(46):39182-92.
• 2012
  Mahiet C, Ergani A, Huot N, Alende N, Azough A, Salvaire F, Bensimon A, Conseiller E, Wain-Hobson S, Labetoulle M, Barradeau S, Structural variability of the herpes simplex virus 1 genome in vitro and in vivo, J. Virol. 2012 Aug;86(16):8592-601.
• 2012
  Henry M, Terzian C, Peeters M, Wain-Hobson S, Vartanian JP, Evolution of the primate APOBEC3A cytidine deaminase gene and identification of related coding regions, PLoS ONE 2012;7(1):e30036.
• 2011
  Hale P, Wain-Hobson S, Weiss RA, Research investment: Vaccine research loses out, Nature 2011 Oct;478(7368):188.
• 2011
  Suspène R, Aynaud MM, Koch S, Pasdeloup D, Labetoulle M, Gaertner B, Vartanian JP, Meyerhans A, Wain-Hobson S, Genetic editing of herpes simplex virus 1 and Epstein-Barr herpesvirus genomes by human APOBEC3 cytidine deaminases in culture and in vivo, J. Virol. 2011 Aug;85(15):7594-602.
• 2011
  Martínez JP, Bocharov G, Ignatovich A, Reiter J, Dittmar MT, Wain-Hobson S, Meyerhans A, Fitness ranking of individual mutants drives patterns of epistatic interactions in HIV-1, PLoS ONE 2011;6(3):e18375.
• 2011
  Suspène R, Aynaud MM, Guétard D, Henry M, Eckhoff G, Marchio A, Pineau P, Dejean A, Vartanian JP, Wain-Hobson S, Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism, Proc. Natl. Acad. Sci. U.S.A. 2011 Mar;108(12):4858-63.
• 2010
  Suspène R, Petit V, Puyraimond-Zemmour D, Aynaud MM, Henry M, Guétard D, Rusniok C, Wain-Hobson S, Vartanian JP, Double-stranded RNA adenosine deaminase ADAR-1-induced hypermutated genomes among inactivated seasonal influenza and live attenuated measles virus vaccines, J. Virol. 2011 Mar;85(5):2458-62.
• 2010
  Rusakiewicz S, Dosset M, Mollier K, Souque P, Charneau P, Wain-Hobson S, Langlade-Demoyen P, Adotévi O, Immunogenicity of a recombinant lentiviral vector carrying human telomerase tumor antigen in HLA-B*0702 transgenic mice, Vaccine 2010 Aug;28(38):6374-81.
• 2010
  Renard M, Henry M, Guétard D, Vartanian JP, Wain-Hobson S, APOBEC1 and APOBEC3 cytidine deaminases as restriction factors for hepadnaviral genomes in non-humans in vivo, J. Mol. Biol. 2010 Jul;400(3):323-34.
• 2010
  Vartanian JP, Henry M, Marchio A, Suspène R, Aynaud MM, Guétard D, Cervantes-Gonzalez M, Battiston C, Mazzaferro V, Pineau P, Dejean A, Wain-Hobson S, Massive APOBEC3 editing of hepatitis B viral DNA in cirrhosis, PLoS Pathog. 2010 May;6(5):e1000928.
• 2010
  Fan J, Ma G, Nosaka K, Tanabe J, Satou Y, Koito A, Wain-Hobson S, Vartanian JP, Matsuoka M, APOBEC3G generates nonsense mutations in human T-cell leukemia virus type 1 proviral genomes in vivo, J. Virol. 2010 Jul;84(14):7278-87.
• 2010
  Adotévi O, Mollier K, Neuveut C, Dosset M, Ravel P, Fridman WH, Tartour E, Charneau P, Wain-Hobson S, Langlade-Demoyen P, Targeting human telomerase reverse transcriptase with recombinant lentivector is highly effective to stimulate antitumor CD8 T-cell immunity in vivo, Blood 2010 Apr;115(15):3025-32.
• 2009
  Gonzalez MC, Suspène R, Henry M, Guétard D, Wain-Hobson S, Vartanian JP, Human APOBEC1 cytidine deaminase edits HBV DNA, Retrovirology 2009;6:96.
• 2009
  Kostrzak A, Cervantes Gonzalez M, Guetard D, Nagaraju DB, Wain-Hobson S, Tepfer D, Pniewski T, Sala M, Oral administration of low doses of plant-based HBsAg induced antigen-specific IgAs and IgGs in mice, without increasing levels of regulatory T cells, Vaccine 2009 Jul;27(35):4798-807.
• 2009
  Petit V, Vartanian JP, Wain-Hobson S, Powerful mutators lurking in the genome, Philos. Trans. R. Soc. Lond., B, Biol. Sci. 2009 Mar;364(1517):705-15.
• 2009
  Henry M, Guétard D, Suspène R, Rusniok C, Wain-Hobson S, Vartanian JP, Genetic editing of HBV DNA by monodomain human APOBEC3 cytidine deaminases and the recombinant nature of APOBEC3G, PLoS ONE 2009;4(1):e4277.
• 2008
  Petit V, Guétard D, Renard M, Keriel A, Sitbon M, Wain-Hobson S, Vartanian JP, Murine APOBEC1 is a powerful mutator of retroviral and cellular RNA in vitro and in vivo, J. Mol. Biol. 2009 Jan;385(1):65-78.
• 2008
  Guetard D, Greco R, Cervantes Gonzalez M, Celli S, Kostrzak A, Langlade-Demoyen P, Sala F, Wain-Hobson S, Sala M, Immunogenicity and tolerance following HIV-1/HBV plant-based oral vaccine administration, Vaccine 2008 Aug;26(35):4477-85.
• 2008
  Suspène R, Renard M, Henry M, Guétard D, Puyraimond-Zemmour D, Billecocq A, Bouloy M, Tangy F, Vartanian JP, Wain-Hobson S, Inversing the natural hydrogen bonding rule to selectively amplify GC-rich ADAR-edited RNAs, Nucleic Acids Res. 2008 Jul;36(12):e72.
• 2008
  Vartanian JP, Guétard D, Henry M, Wain-Hobson S, Evidence for editing of human papillomavirus DNA by APOBEC3 in benign and precancerous lesions, Science 2008 Apr;320(5873):230-3.
• 2007
  Terzian C, Henry M, Meyerhans A, Wain-Hobson S, Vartanian JP, Induction of mutations in Drosophila melanogaster gypsy retroelements by modulation of intracellular deoxynucleoside triphosphate pools in vivo, J. Virol. 2007 May;81(9):4900-3.
• 2006
  Suspène R, Rusniok C, Vartanian JP, Wain-Hobson S, Twin gradients in APOBEC3 edited HIV-1 DNA reflect the dynamics of lentiviral replication, Nucleic Acids Res. 2006;34(17):4677-84.
• 2006
  Michel M, Lone YC, Centlivre M, Roux P, Wain-Hobson S, Sala M, Optimisation of secretion of recombinant HBsAg virus-like particles: Impact on the development of HIV-1/HBV bivalent vaccines, Vaccine 2007 Feb;25(10):1901-11.
• 2006
  Centlivre M, Sommer P, Michel M, Ho Tsong Fang R, Gofflo S, Valladeau J, Schmitt N, Wain-Hobson S, Sala M, The HIV-1 clade C promoter is particularly well adapted to replication in the gut in primary infection, AIDS 2006 Mar;20(5):657-66.
• 2006
  Sala M, Centlivre M, Wain-Hobson S, Clade-specific differences in active viral replication and compartmentalization, Curr Opin HIV AIDS 2006 Mar;1(2):108-14.
• 2006
  Delebecque F, Suspène R, Calattini S, Casartelli N, Saïb A, Froment A, Wain-Hobson S, Gessain A, Vartanian JP, Schwartz O, Restriction of foamy viruses by APOBEC cytidine deaminases, J. Virol. 2006 Jan;80(2):605-14.
• 2005
  Dumaurier MJ, Gratton S, Wain-Hobson S, Cheynier R, The majority of human immunodeficiency virus type 1 particles present within splenic germinal centres are produced locally, J. Gen. Virol. 2005 Dec;86(Pt 12):3369-73.
• 2005
  Mahieux R, Suspène R, Delebecque F, Henry M, Schwartz O, Wain-Hobson S, Vartanian JP, Extensive editing of a small fraction of human T-cell leukemia virus type 1 genomes by four APOBEC3 cytidine deaminases, J. Gen. Virol. 2005 Sep;86(Pt 9):2489-94.
• 2005
  Centlivre M, Sommer P, Michel M, Ho Tsong Fang R, Gofflo S, Valladeau J, Schmitt N, Thierry F, Hurtrel B, Wain-Hobson S, Sala M, HIV-1 clade promoters strongly influence spatial and temporal dynamics of viral replication in vivo, J. Clin. Invest. 2005 Feb;115(2):348-58.
• 2005
  Suspène R, Henry M, Guillot S, Wain-Hobson S, Vartanian JP, Recovery of APOBEC3-edited human immunodeficiency virus G->A hypermutants by differential DNA denaturation PCR, J. Gen. Virol. 2005 Jan;86(Pt 1):125-9.
• 2004
  Pineau P, Henry M, Suspène R, Marchio A, Dettai A, Debruyne R, Petit T, Lécu A, Moisson P, Dejean A, Wain-Hobson S, Vartanian JP, A universal primer set for PCR amplification of nuclear histone H4 genes from all animal species, Mol. Biol. Evol. 2005 Mar;22(3):582-8.
• 2004
  Suspène R, Sommer P, Henry M, Ferris S, Guétard D, Pochet S, Chester A, Navaratnam N, Wain-Hobson S, Vartanian JP, APOBEC3G is a single-stranded DNA cytidine deaminase and functions independently of HIV reverse transcriptase, Nucleic Acids Res. 2004;32(8):2421-9.
• 2004
  Blancou P, Chenciner N, Ho Tsong Fang R, Monceaux V, Cumont MC, Guétard D, Hurtrel B, Wain-Hobson S, Simian immunodeficiency virus promoter exchange results in a highly attenuated strain that protects against uncloned challenge virus, J. Virol. 2004 Feb;78(3):1080-92.
• 2003
  Vartanian JP, Sommer P, Wain-Hobson S, Death and the retrovirus, Trends Mol Med 2003 Oct;9(10):409-13.
• 2003
  Wain-Hobson S, Renoux-Elbé C, Vartanian JP, Meyerhans A, Network analysis of human and simian immunodeficiency virus sequence sets reveals massive recombination resulting in shorter pathways, J. Gen. Virol. 2003 Apr;84(Pt 4):885-95.
• 2002
  Vartanian JP, Pineau P, Henry M, Hamilton WD, Muller MN, Wrangham RW, Wain-Hobson S, Identification of a hepatitis B virus genome in wild chimpanzees (Pan troglodytes schweinfurthi) from East Africa indicates a wide geographical dispersion among equatorial African primates, J. Virol. 2002 Nov;76(21):11155-8.
• 2002
  Vartanian JP, Wain-Hobson S, Analysis of a library of macaque nuclear mitochondrial sequences confirms macaque origin of divergent sequences from old oral polio vaccine samples, Proc. Natl. Acad. Sci. U.S.A. 2002 May;99(11):7566-9.
• 2002
  Vartanian JP, Henry M, Wain-Hobson S, Sustained G–>A hypermutation during reverse transcription of an entire human immunodeficiency virus type 1 strain Vau group O genome, J. Gen. Virol. 2002 Apr;83(Pt 4):801-5.
• 2002
  Renoux-Elbé C, Cheynier R, Wain-Hobson S, Phylogeny derived from coding retroviral genome organization, J. Mol. Evol. 2002 Mar;54(3):376-85.