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Guides
  • 2025
    Josée Guirouilh-Barbat, Iman Litchy Boueya, Camille Gelot, Gaëlle Pennarun, Christine Granotier-Beckers, Elodie Dardillac, Wei Yu, Chloé Lescale, Emilie Rass, Olivier Ariste, Nicolas Siaud, Benjamin Renouf, Armel Millet, Nadine Puget, Pascale Bertrand, Pierre de la Grange, Erika Brunet, Ludovic Deriano, Bernard S Lopez, Genome rearrangements induced by the stimulation of end-joining of DNA double strand breaks through multiple phosphorylation of MRE11 by the kinase PKB/AKT1, Nucleic Acids Res. 2025 Jun 6;53(11):gkaf468. doi: 10.1093/nar/gkaf468..
  • 2025
    Chloé Lescale, Timea Marton, Amaury Vaysse, Guillaume Rode, Estelle Vincendeau, Alice Libri, François Dossin, Ludovic Deriano, CST Is Epistatic With Shieldin to Limit DNA Double-Strand Break End Resection and Promote Repair During Igh Class Switch Recombination, Eur J Immunol . 2025 Apr;55(4):e202451585. doi: 10.1002/eji.202451585.
  • 2022
    Vincendeau E, Wei W, Zhang X, Planchais C, Yu W, Lenden-Hasse H, Cokelaer T, Pipoli da Fonseca J, Mouquet H, Adams DJ, Alt FW, Jackson SP, Balmus G, Lescale C, Deriano L, , SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination., Nat Commun 2022 Jun; 13(1): 3707.
  • 2021
    Mélanie Rogier, Jacques Moritz, Isabelle Robert, Chloé Lescale, Vincent Heyer, Arthur Abello, Ophélie Martin, Katia Capitani, Morgane Thomas, Anne-Sophie Thomas-Claudepierre, Brice Laffleur, Florence Jouan, Eric Pinaud, Karin Tarte, Michel Cogné, Silvestro G Conticello, Evi Soutoglou, Ludovic Deriano, Bernardo Reina-San-Martin , Fam72a enforces error-prone DNA repair during antibody diversification, Nature . 2021 Dec;600(7888):329-333. .
  • 2020
    Yu W, Lescale C, Babin L, Bedora-Faure M, Lenden-Hasse H, Baron L, Demangel C, Yelamos J, Brunet E, Deriano L, , Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ., Nat Commun 2020 Oct; 11(1): 5239.
  • 2019
    Galindo-Campos MA, Bedora-Faure M, Farrés J, Lescale C, Moreno-Lama L, Martínez C, Martín-Caballero J, Ampurdanés C, Aparicio P, Dantzer F, Cerutti A, Deriano L*, Yélamos J*, Coordinated signals from the DNA repair enzymes PARP-1 and PARP-2 promotes B-cell development and function, Cell Death Differ. 2019 Apr 17. .
  • 2018
    Dev H, Chiang TW#, Lescale C#, de Krijger I#, Martin AG, Pilger D, Coates J, Sczaniecka-Clift M, Wei W, Ostermaier M, Herzog M, Lam J, Shea A, Demir M, Wu Q, Yang F, Fu B, Lai Z, Balmus G, Belotserkovskaya R, Serra V, O'Connor MJ, Bruna A, Beli P, Pellegrini L, Caldas C, Deriano L*, Jacobs JJL*, Galanty Y*, Jackson SP.*, Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells., Nat Cell Biol. 2018 Aug;20(8):954-965. doi: 10.1038/s41556-018-0140-1. Epub 2018 Jul 18..
  • 2017
    Lenden Hasse H, Lescale C, Bianchi JJ, Yu W, Bedora-Faure M, Deriano L, Generation and CRISPR/Cas9 editing of transformed progenitor B cells as a pseudo-physiological system to study DNA repair gene function in V(D)J recombination, J. Immunol. Methods 2017 12;451:71-77.
  • 2017
    Lescale C, Lenden Hasse H, Deriano L, [Paralogy and redundancy: maintaining genome integrity during V(D)J recombination], Med Sci (Paris) 2017 May;33(5):474-477.
  • 2016
    Chloé Lescale and Ludovic Deriano, The RAG Recombinase: Beyond Breaking, Mech Ageing Dev. 2016 Nov 15. pii: S0047-6374(16)30263-9. doi: 10.1016/j.mad.2016.11.003. [Epub ahead of print].
  • 2016
    Gabriel Balmus, Ana C. Barros, Paul W.G. Wijnhoven, Chloé Lescale, Hélène Lenden Hasse, Katharina Boroviak, Carlos le Sage, Brendan Doe, Anneliese O. Speak, Antonella Galli, Matt Jacobsen, Ludovic Deriano, David J. Adams, Andrew N. Blackford and Stephen P. Jackson, Synthetic lethality between PAXX and XLF in mammalian development, Genes Dev. 2016 Oct 1;30(19):2152-2157..
  • 2016
    Lescale C., and Deriano L, V(D)J Recombination: Orchestrating Diversity without Damage., Lescale C., and Deriano L., V(D)J Recombination: Orchestrating Diversity without Damage. In: Ralph A Bradshaw and Philip D Stahl (Editors-in-Chief), Encyclopedia of Cell Biology, Vol 3, Waltham, MA: Academic Press, 2016, pp. 550-566..
  • 2016
    Chloe Lescale,* Helene Lenden Hasse,* Andrew N. Blackford, Gabriel Balmus, Joy J. Bianchi, Wei Yu, Lea Bacoccina, Angelique Jarade, Christophe Clouin, Rohan Sivapalan, Bernardo Reina-San-Martin, Stephen P. Jackson and Ludovic Deriano, Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination, Cell Rep. 2016 Sep 13;16(11):2967-79. doi: 10.1016/j.celrep.2016.08.069. Epub 2016 Sep 2..
  • 2016
    Lescale C, Abramowski V, Bedora-Faure M, Murigneux V, Vera G, Roth DB, Revy P, de Villartay JP, Deriano L, RAG2 and XLF/Cernunnos interplay reveals a novel role for the RAG complex in DNA repair, Nat Commun 2016;7:10529.
  • 2015
    Granito RN, Bouleftour W, Sabido O, Lescale C, Thomas M, Aubin JE, Goodhardt M, Vico L, Malaval L, Absence of bone sialoprotein (BSP) alters profoundly hematopoiesis and upregulates osteopontin, J. Cell. Physiol. 2015 Jun;230(6):1342-51.
  • 2014
    Lescale C, Schenten V, Djeghloul D, Bennabi M, Gaignier F, Vandamme K, Strazielle C, Kuzniak I, Petite H, Dosquet C, Frippiat JP, Goodhardt M, Hind limb unloading, a model of spaceflight conditions, leads to decreased B lymphopoiesis similar to aging, FASEB J. 2015 Feb;29(2):455-63.
  • 2010
    Lescale C, Dias S, Maës J, Cumano A, Szabo P, Charron D, Weksler ME, Dosquet C, Vieira P, Goodhardt M, Reduced EBF expression underlies loss of B-cell potential of hematopoietic progenitors with age, Aging Cell 2010 Jun;9(3):410-9.
  • 2008
    Warburton PE, Hasson D, Guillem F, Lescale C, Jin X, Abrusan G, Analysis of the largest tandemly repeated DNA families in the human genome, BMC Genomics 2008;9:533.
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