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Guides
  • 2022
    Rifflet A, Demangel C, Guenin-Macé L, , Mycolactone Purification from M. ulcerans Cultures and HPLC-Based Approaches for Mycolactone Quantification in Biological Samples., Methods Mol Biol 2022 ; 2387(): 117-130.
  • 2021
    Laval T, Pedró-Cos L, Malaga W, Guenin-Macé L, Pawlik A, Mayau V, Yahia-Cherbal H, Delos O, Frigui W, Bertrand-Michel J, Guilhot C, Demangel C, , De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis., Elife 2021 Dec; 10(): .
  • 2021
    Tello Rubio B, Bugault F, Baudon B, Raynal B, Brûlé S, Morel JD, Saint-Auret S, Blanchard N, Demangel C, Guenin-Macé L, , Molecular Mechanisms Underpinning the Circulation and Cellular Uptake of Mycobacterium ulcerans Toxin Mycolactone., Front Pharmacol 2021 ; 12(): 733496.
  • 2020
    Chevalier G, Siopi E, Guenin-Macé L, Pascal M, Laval T, Rifflet A, Boneca IG, Demangel C, Colsch B, Pruvost A, Chu-Van E, Messager A, Leulier F, Lepousez G, Eberl G, Lledo PM, , Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system., Nat Commun 2020 12; 11(1): 6363.
  • 2020
    Colucci-Guyon E, Rifflet A, Saint-Auret S, da Costa A, Boucontet L, Laval T, Prehaud C, Blanchard N, Levraud JP, Boneca IG, Demangel C, Guenin-Macé L, , Spatiotemporal analysis of mycolactone distribution in vivo reveals partial diffusion in the central nervous system., PLoS Negl Trop Dis 2020 Dec; 14(12): e0008878.
  • 2020
    Guenin-Macé L, Morel JD, Doisne JM, Schiavo A, Boulet L, Mayau V, Goncalves P, Duchatelet S, Hovnanian A, Bondet V, Duffy D, Ungeheuer MN, Delage M, Nassif A, Di Santo JP, Demangel C, , Dysregulation of tryptophan catabolism at the host-skin microbiota interface in Hidradenitis Suppurativa., 2020 Sep 24;140598..
  • 2017
    Isaac C, Mauborgne A, Grimaldi A, Ade K, Pohl M, Limatola C, Boucher Y, Demangel C, Guenin-Macé L, Mycolactone displays anti-inflammatory effects on the nervous system, PLoS Negl Trop Dis 2017 Nov;11(11):e0006058.
  • 2015
    Guenin-Macé L, Baron L, Chany AC, Tresse C, Saint-Auret S, Jönsson F, Le Chevalier F, Bruhns P, Bismuth G, Hidalgo-Lucas S, Bisson JF, Blanchard N, Demangel C, , Shaping mycolactone for therapeutic use against inflammatory disorders., Sci Transl Med 2015 May; 7(289): 289ra85.
  • 2014
    Chany AC, Veyron-Churlet R, Tresse C, Mayau V, Casarotto V, Le Chevalier F, Guenin-Macé L, Demangel C, Blanchard N, Synthetic variants of mycolactone bind and activate Wiskott-Aldrich syndrome proteins, J. Med. Chem. 2014 Sep;57(17):7382-95.
  • 2014
    Guenin-Macé L, Oldenburg R, Chrétien F, Demangel C, Pathogenesis of skin ulcers: lessons from the Mycobacterium ulcerans and Leishmania spp. pathogens, Cell. Mol. Life Sci. 2014 Jul;71(13):2443-50.
  • 2013
    Guenin-Macé L, Veyron-Churlet R, Thoulouze MI, Romet-Lemonne G, Hong H, Leadlay PF, Danckaert A, Ruf MT, Mostowy S, Zurzolo C, Bousso P, Chrétien F, Carlier MF, Demangel C, Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation, J. Clin. Invest. 2013 Apr;123(4):1501-12.
  • 2011
    Chany AC, Casarotto V, Schmitt M, Tarnus C, Guenin-Macé L, Demangel C, Mirguet O, Eustache J, Blanchard N, A diverted total synthesis of mycolactone analogues: an insight into Buruli ulcer toxins, Chemistry 2011 Dec;17(51):14413-9.
  • 2011
    Sarfo FS, Le Chevalier F, Aka N, Phillips RO, Amoako Y, Boneca IG, Lenormand P, Dosso M, Wansbrough-Jones M, Veyron-Churlet R, Guenin-Macé L, Demangel C, Mycolactone diffuses into the peripheral blood of Buruli ulcer patients–implications for diagnosis and disease monitoring, PLoS Negl Trop Dis 2011 Jul;5(7):e1237.
  • 2011
    Guenin-Macé L, Carrette F, Asperti-Boursin F, Le Bon A, Caleechurn L, Di Bartolo V, Fontanet A, Bismuth G, Demangel C, , Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression., Proc. Natl. Acad. Sci. U.S.A. 2011 Aug; 108(31): 12833-8.
  • 2009
    Guenin-Macé L, Siméone R, Demangel C, Lipids of pathogenic Mycobacteria: contributions to virulence and host immune suppression, Transbound Emerg Dis 2009 Aug;56(6-7):255-68.
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