• 2025
  Pierre Authié, Philippe Souque, Fanny Moncoq, Amandine Noirat, Catherine Blanc, Sylvain Ciret, Maryline Bourgine, David Hardy, Françoise Guinet, Laleh Majlessi, Pierre Charneau, Kirill Nemirov, Lentiviral vector-based T-cell vaccines against Zika and yellow fever viruses, Vaccine.
• 2025
  Vesin B, Fert I, Noirat A, Authié P, Ciret S, Blanc C, Vitrenko Y, Charneau P, Majlessi L, Anna F, Optimized lentiviral backbone induces robust and diverse T cell immunity against neoantigens to counteract tumor heterogeneity., NPJ Vaccines 2025 Jul; 10(1): 143.
• 2024
  Fert I, Douguet L, Vesin B, Moncoq F, Noirat A, Authié P, Ciret S, Le Chevalier F, Blanc C, Vitrenko Y, Charneau P, Majlessi L, Anna F, T-cell immunity induced and reshaped by an anti-HPV immuno-oncotherapeutic lentiviral vector., NPJ Vaccines 2024 Jun; 9(1): 102.
• 2024
  Brunet J, Choucha Z, Gransagne M, Tabbal H, Ku M-W, Buchrieser J, Fernandes P, Batalie D, Lopez J, Ma L, Dufour E, Simon E, Hardy D, Petres S, Guinet F, Strick-Marchand H, Monot M, Charneau P, Majlessi L, Duprex WP, Gerke C, Martin A, Escriou N, A measles-vectored vaccine candidate expressing prefusion-stabilized SARS-CoV-2 spike protein brought to phase I/II clinical trials: candidate selection in a preclinical murine model., J Virol 2024 Apr; (): e0169323.
• 2023
  Douguet L, Fert I, Lopez J, Vesin B, Le Chevalier F, Moncoq F, Authié P, Nguyen TM, Noirat A, Névo F, Blanc C, Bourgine M, Hardy D, Anna F, Majlessi L, Charneau P, Full eradication of pre-clinical human papilloma virus-induced tumors by a lentiviral vaccine., EMBO Mol Med 2023 Sep; (): e17723.
• 2023
  Domenger A, Ricci D, Mayau V, Majlessi L, Marcireau C, Dadaglio G, Demangel C, Sec61 blockade therapy overrides resistance to proteasome inhibitors and immunomodulatory drugs in multiple myeloma., Front Oncol 2023 ; 13(): 1110916.
• 2023
  Nemirov K, Authié P, Souque P, Moncoq F, Noirat A, Blanc C, Bourgine M, Majlessi L, Charneau P, Preclinical proof of concept of a tetravalent lentiviral T-cell vaccine against dengue viruses., Front Immunol 2023 ; 14(): 1208041.
• 2022
  Benjamin Vesin 1 , Pierre Authié 1 , Catherine Blanc 1 , Ingrid Fert 1 , Amandine Noirat 1 , Fabien Le Chevalier 1 , Yu Wei 1 , Min-Wen Ku 1 , Kirill Nemirov 1 , François Anna 1 , David Hardy 2 , Cyril Planchais 3 , Hugo Mouquet 3 , Françoise Guinet 4 , Pierre Charneau 1 , Laleh Majlessi 1 , Maryline Bourgine 1, Full-Lung Prophylaxis against SARS-CoV-2 by One-Shot or Booster Intranasal Lentiviral Vaccination in Syrian Golden Hamsters, Vaccines (Basel).
• 2022
  Anna F, Lopez J, Moncoq F, Blanc C, Authié P, Noirat A, Fert I, Souque P, Nevo F, Pawlik A, Hardy D, Goyard S, Hudrisier D, Brosch R, Guinet F, Neyrolles O, Charneau P, Majlessi L, , A lentiviral vector expressing a dendritic cell-targeting multimer induces mucosal anti-mycobacterial CD4+ T-cell immunity., Mucosal Immunol 2022 Sep; (): .
• 2022
  Lopez J, Anna F, Authié P, Pawlik A, Ku MW, Blanc C, Souque P, Moncoq F, Noirat A, Hardy D, Sougakoff W, Brosch R, Guinet F, Charneau P, Majlessi L, , A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity., Cell Rep 2022 Jul; 40(4): 111142.
• 2022
  Vesin B, Lopez J, Noirat A, Authié P, Fert I, Le Chevalier F, Moncoq F, Nemirov K, Blanc C, Planchais C, Mouquet H, Guinet F, Hardy D, Vives FL, Gerke C, Anna F, Bourgine M, Majlessi L, Charneau P, , An intranasal lentiviral booster reinforces the waning mRNA vaccine-induced SARS-CoV-2 immunity that it targets to lung mucosa., Mol Ther 2022 Apr; (): .
• 2021
  Ku MW, Authié P, Bourgine M, Anna F, Noirat A, Moncoq F, Vesin B, Nevo F, Lopez J, Souque P, Blanc C, Fert I, Chardenoux S, Lafosse L, Cussigh D, Hardy D, Nemirov K, Guinet F, Langa Vives F, Majlessi L, Charneau P, , Brain cross-protection against SARS-CoV-2 variants by a lentiviral vaccine in new transgenic mice., EMBO Mol Med 2021 12; 13(12): e14459.
• 2019
  Machelart A, Salzano G, Li X, Demars A, Debrie AS, Menendez-Miranda M, Pancani E, Jouny S, Hoffmann E, Deboosere N, Belhaouane I, Rouanet C, Simar S, Talahari S, Giannini V, Villemagne B, Flipo M, Brosch R, Nesslany F, Deprez B, Muraille E, Locht C, Baulard AR, Willand N, Majlessi L, Gref R, Brodin P, Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers Against Tuberculosis, ACS Nano 2019 Mar;.
• 2018
  Ates LS, Dippenaar A, Sayes F, Pawlik A, Bouchier C, Ma L, Warren RM, Sougakoff W, Majlessi L, van Heijst JWJ, Brossier F, Brosch R, Unexpected genomic and phenotypic diversity of Mycobacterium africanum Lineage 5 affects drug resistance, protein secretion and immunogenicity, Genome Biol Evol 2018 Jul;.
• 2018
  Ates LS, Sayes F, Frigui W, Ummels R, Damen MPM, Bottai D, Behr MA, van Heijst JWJ, Bitter W, Majlessi L, Brosch R, RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection, PLoS Pathog. 2018 Jun;14(6):e1007139.
• 2018
  Sayes F, Blanc C, Ates LS, Deboosere N, Orgeur M, Le Chevalier F, Gröschel MI, Frigui W, Song OR, Lo-Man R, Brossier F, Sougakoff W, Bottai D, Brodin P, Charneau P, Brosch R, Majlessi L, Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors, Cell Rep 2018 Apr;23(4):1072-1084.
• 2018
  Laencina L, Dubois V, Le Moigne V, Viljoen A, Majlessi L, Pritchard J, Bernut A, Piel L, Roux AL, Gaillard JL, Lombard B, Loew D, Rubin EJ, Brosch R, Kremer L, Herrmann JL, Girard-Misguich F, Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus, Proc. Natl. Acad. Sci. U.S.A. 2018 01;115(5):E1002-E1011.
• 2017
  Majlessi, L & Brosch R, Un nouveau concept pour améliorer le vaccin antituberculeux, Planet-Vie (Ressources en sciences de la vie pour les enseignants), Lundi 28 août 2017.
• 2017
  Gröschel MI, Sayes F, Shin SJ, Frigui W, Pawlik A, Orgeur M, Canetti R, Honoré N, Simeone R, van der Werf TS, Bitter W, Cho SN, Majlessi L, Brosch R,, Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection, Cell Reports 2017, 18, (11), 2752–2765.
• 2017
  Majlessi L, Sayes F, Bureau JF, Pawlik A, Michel V, Jouvion G, Huerre M, Severgnini M, Consolandi C, Peano C, Brosch R, Touati E, Leclerc C, Colonization with Helicobacter is concomitant with modified gut microbiota and drastic failure of the immune control of Mycobacterium tuberculosis, Mucosal Immunol 2017 Sep;10(5):1178-1189.
• 2016
  Roux AL, Viljoen A, Bah A, Simeone R, Bernut A, Laencina L, Deramaudt T, Rottman M, Gaillard JL, Majlessi L, Brosch R, Girard-Misguich F, Vergne I, de Chastellier C, Kremer L, Herrmann JL, The distinct fate of smooth and rough Mycobacterium abscessus variants inside macrophages, Open Biol 2016 Nov;6(11).
• 2016
  Gröschel MI, Sayes F, Simeone R, Majlessi L, Brosch R, ESX secretion systems: mycobacterial evolution to counter host immunity, Nat. Rev. Microbiol. 2016, 14(11):677-691..
• 2016
  Sayes F, Pawlik A, Frigui W, Gröschel MI, Crommelynck S, Fayolle C, Cia F, Bancroft GJ, Bottai D, Leclerc C, Brosch R, Majlessi L., CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection, PLoS Pathog. 2016 Jul 28;12(7):e1005770. doi: 10.1371/journal.ppat.1005770..
• 2016
  Simeone R, Majlessi L, Enninga J, Brosch R, Perspectives on mycobacterial vacuole-to-cytosol translocation: the importance of cytosolic access, Cell. Microbiol. 2016 May;.
• 2016
  Singh VK, Berry L, Bernut A, Singh S, Carrère-Kremer S, Viljoen A, Alibaud L, Majlessi L, Brosch R, Chaturvedi V, Geurtsen J, Drancourt M, Kremer L, A unique PE_PGRS protein inhibiting host cell cytosolic defenses and sustaining full virulence of Mycobacterium marinum in multiple hosts, Cell. Microbiol. 2016 Apr;.
• 2016
  Eva C. Boritsch, Wafa Frigui, Alessandro Cascioferro, Wladimir Malaga, Gilles Etienne, Françoise Laval, Alexandre Pawlik, Fabien Le Chevalier, Mickael Orgeur, Laurence Ma, Christiane Bouchier, Timothy P. Stinear, Philip Supply, Laleh Majlessi, Mamadou Daffé, Christophe Guilhot & Roland Brosch, pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence, Nature Microbiol. 1, 15019 (2016).
• 2015
  Le Chevalier F, Cascioferro A, Frigui W, Pawlik A, Boritsch EC, Bottai D, Majlessi L, Herrmann JL, Brosch R, Revisiting the role of phospholipases C in virulence and the lifecycle of Mycobacterium tuberculosis, Sci Rep 2015;5:16918.
• 2015
  Majlessi L, Brosch R, Mycobacterium tuberculosis Meets the Cytosol: The Role of cGAS in Anti-mycobacterial Immunity, Cell Host Microbe 2015 Jun;17(6):733-5.
• 2015
  Majlessi L, Prados-Rosales R, Casadevall A, Brosch R, Release of mycobacterial antigens, Immunol. Rev. 2015 Mar;264(1):25-45.
• 2015
  Simeone R, Bottai D, Frigui W, Majlessi L, Brosch R, ESX/type VII secretion systems of mycobacteria: Insights into evolution, pathogenicity and protection, Tuberculosis (Edinb) 2015 Feb;.
• 2015
  Simeone R, Sayes F, Song O, Gröschel MI, Brodin P, Brosch R, Majlessi L, Cytosolic access of Mycobacterium tuberculosis: critical impact of phagosomal acidification control and demonstration of occurrence in vivo, PLoS Pathog. 2015 Feb;11(2):e1004650.
• 2013
  Supply P, Marceau M, Mangenot S, Roche D, Rouanet C, Khanna V, Majlessi L, Criscuolo A, Tap J, Pawlik A, Fiette L, Orgeur M, Fabre M, Parmentier C, Frigui W, Simeone R, Boritsch EC, Debrie AS, Willery E, Walker D, Quail MA, Ma L, Bouchier C, Salvignol G, Sayes F, Cascioferro A, Seemann T, Barbe V, Locht C, Gutierrez MC, Leclerc C, Bentley SD, Stinear TP, Brisse S, Médigue C, Parkhill J, Cruveiller S, Brosch R, Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis, Nat. Genet. 2013 Feb;45(2):172-9.
• 2012
  Sayes F, Sun L, Di Luca M, Simeone R, Degaiffier N, Fiette L, Esin S, Brosch R, Bottai D, Leclerc C, Majlessi L, Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 type VII secretion: encoded PE-PPE proteins predicts vaccine potential, Cell Host Microbe 2012 Apr;11(4):352-63.