• 2025
  Alvarez F, de Melo GD, Larrous F, Kergoat L, Boëda B, Michel V, Seilhean D, Tichit M, Hing D, Hardy D, Kornobis E, Bourhy H, Wolff N, Caillet-Saguy C, The SARS-CoV-2 envelope PDZ binding motif acts as a virulence factor disrupting host’s epithelial cell-cell junctions., Cell Mol Biol Lett 2025 Jul; 30(1): 80.
• 2023
  de Melo GD, Perraud V, Alvarez F, Vieites-Prado A, Kim S, Kergoat L, Coleon A, Trüeb BS, Tichit M, Piazza A, Thierry A, Hardy D, Wolff N, Munier S, Koszul R, Simon-Lorière E, Thiel V, Lecuit M, Lledo PM, Renier N, Larrous F, Bourhy H, Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants., Nat Commun 2023 Jul; 14(1): 4485.
• 2023
  Genera M, Colcombet-Cazenave B, Croitoru A, Raynal B, Mechaly A, Caillet J, Haouz A, Wolff N, Caillet-Saguy C, Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity., Front Mol Biosci 2023 ; 10(): 1192621.
• 2022
  Zhu Y, Alvarez F, Wolff N, Mechaly A, Brûlé S, Neitthoffer B, Etienne-Manneville S, Haouz A, Boëda B, Caillet-Saguy C, , Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins., Front Microbiol 2022 ; 13(): 829094.
• 2022
  Colcombet-Cazenave B, Cordier F, Zhu Y, Bouvier G, Litsardaki E, Laserre L, Prevost MS, Raynal B, Caillet-Saguy C, Wolff N, , Deciphering the Molecular Interaction Between the Adhesion G Protein-Coupled Receptor ADGRV1 and its PDZ-Containing Regulator PDZD7., Front Mol Biosci 2022 ; 9(): 923740.
• 2021
  Caillet-Saguy C, Wolff N, , PDZ-Containing Proteins Targeted by the ACE2 Receptor., Viruses 2021 11; 13(11): .
• 2021
  Caillet-Saguy C, Durbesson F, Rezelj VV, Gogl G, Dinh Tran Q, Twizere JC, Vignuzzi M, Vincentelli R, Wolff N, , Host PDZ-containing proteins targeted by SARS-Cov-2., FEBS J 2021 Apr; (): .
• 2021
  Colcombet-Cazenave B, Druart K, Bonnet C, Petit C, Spérandio O, Guglielmini J, Wolff N, , Phylogenetic analysis of Harmonin homology domains., BMC Bioinformatics 2021 Apr; 22(1): 190.
• 2021
  Giraud E, Del Val CO, Caillet-Saguy C, Zehrouni N, Khou C, Caillet J, Jacob Y, Pardigon N, Wolff N, Role of PDZ-binding motif from West Nile virus NS5 protein on viral replication., Sci Rep 2021 Feb; 11(1): 3266.
• 2021
  Genera M, Quioc-Salomon B, Nourisson A, Colcombet-Cazenave B, Haouz A, Mechaly A, Matondo M, Duchateau M, König A, Windisch MP, Neuveut C, Wolff N, Caillet-Saguy C, , Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein., Sci Rep 2021 Jan; 11(1): 944.
• 2021
  Caillet-Saguy C, Brûlé S, Wolff N, Raynal B, , PDZ Sample Quality Assessment by Biochemical and Biophysical Characterizations., Methods Mol Biol 2021 ; 2256(): 89-124.
• 2021
  Spill YG, Karami Y, Maisonneuve P, Wolff N, Nilges M, , Automatic Bayesian Weighting for SAXS Data., Front Mol Biosci 2021 ; 8(): 671011.
• 2020
  Boucher S, Tai FWJ, Delmaghani S, Lelli A, Singh-Estivalet A, Dupont T, Niasme-Grare M, Michel V, Wolff N, Bahloul A, Bouyacoub Y, Bouccara D, Fraysse B, Deguine O, Collet L, Thai-Van H, Ionescu E, Kemeny JL, Giraudet F, Lavieille JP, Devèze A, Roudevitch-Pujol AL, Vincent C, Renard C, Franco-Vidal V, Thibult-Apt C, Darrouzet V, Bizaguet E, Coez A, Aschard H, Michalski N, Lefevre GM, Aubois A, Avan P, Bonnet C, Petit C, , Ultrarare heterozygous pathogenic variants of genes causing dominant forms of early-onset deafness underlie severe presbycusis., Proc Natl Acad Sci U S A 2020 12; 117(49): 31278-31289.
• 2020
  Zhu Y, Delhommel F, Cordier F, Lüchow S, Mechaly A, Colcombet-Cazenave B, Girault V, Pepermans E, Bahloul A, Gautier C, Brûlé S, Raynal B, Hoos S, Haouz A, Caillet-Saguy C, Ivarsson Y, Wolff N, , Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners., J Mol Biol 2020 11; 432(22): 5920-5937.
• 2020
  Michel V, Pepermans E, Boutet de Monvel J, England P, Nouaille S, Aghaie A, Delhommel F, Wolff N, Perfettini I, Hardelin JP, Petit C, Bahloul A, , Interaction of protocadherin-15 with the scaffold protein whirlin supports its anchoring of hair-bundle lateral links in cochlear hair cells., Sci Rep 2020 Oct; 10(1): 16430.
• 2020
  Gautier C, Troilo F, Cordier F, Malagrinò F, Toto A, Visconti L, Zhu Y, Brunori M, Wolff N, Gianni S, , Hidden kinetic traps in multidomain folding highlight the presence of a misfolded but functionally competent intermediate., Proc Natl Acad Sci U S A 2020 08; 117(33): 19963-19969.
• 2020
  Gogl G, Jane P, Caillet-Saguy C, Kostmann C, Bich G, Cousido-Siah A, Nyitray L, Vincentelli R, Wolff N, Nomine Y, Sluchanko NN, Trave G, , Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study., Structure 2020 07; 28(7): 747-759.e3.
• 2020
  Jané P, Gógl G, Kostmann C, Bich G, Girault V, Caillet-Saguy C, Eberling P, Vincentelli R, Wolff N, Travé G, Nominé Y, , Interactomic affinity profiling by holdup assay: Acetylation and distal residues impact the PDZome-binding specificity of PTEN phosphatase., PLoS One 2020 ; 15(12): e0244613.
• 2019
  Caillet J, Baron B, Boni IV, Caillet-Saguy C, Hajnsdorf E, , Identification of protein-protein and ribonucleoprotein complexes containing Hfq., Sci Rep 2019 Oct; 9(1): 14054.
• 2019
  Khan Z, Terrien E, Delhommel F, Lefebvre-Omar C, Bohl D, Vitry S, Bernard C, Ramirez J, Chaffotte A, Ricquier K, Vincentelli R, Buc H, Prehaud C, Wolff N, Lafon M, Structure-based optimization of a PDZ-binding motif within a viral peptide stimulates neurite outgrowth, J. Biol. Chem. 2019 Sep;294(37):13755-13768.
• 2019
  Genera M, Samson D, Raynal B, Haouz A, Baron B, Simenel C, Guerois R, Wolff N, Caillet-Saguy C, , Structural and functional characterization of the PDZ domain of the human phosphatase PTPN3 and its interaction with the human papillomavirus E6 oncoprotein., Sci Rep 2019 05; 9(1): 7438.
• 2019
  Duhoo Y, Girault V, Turchetto J, Ramond L, Durbesson F, Fourquet P, Nominé Y, Cardoso V, Sequeira AF, Brás JLA, Fontes CMGA, Travé G, Wolff N, Vincentelli R, High-Throughput Production of a New Library of Human Single and Tandem PDZ Domains Allows Quantitative PDZ-Peptide Interaction Screening Through High-Throughput Holdup Assay, Methods Mol. Biol. 2019;2025:439-476.
• 2018
  Delhommel F, Cordier F, Saul F, Chataigner L, Haouz A, Wolff N, Structural plasticity of the HHD2 domain of whirlin., FEBS J 2018 Oct; 285(20): 3738-3752.
• 2017
  Bruzzoni-Giovanelli H, Alezra V, Wolff N, Dong CZ, Tuffery P, Rebollo A, Interfering peptides targeting protein-protein interactions: the next generation of drugs?, Drug Discov. Today 2018 Feb;23(2):272-285.
• 2017
  Delhommel F, Cordier F, Bardiaux B, Bouvier G, Colcombet-Cazenave B, Brier S, Raynal B, Nouaille S, Bahloul A, Chamot-Rooke J, Nilges M, Petit C, Wolff N, Structural Characterization of Whirlin Reveals an Unexpected and Dynamic Supramodule Conformation of Its PDZ Tandem, Structure 2017 11;25(11):1645-1656.e5.
• 2017
  Caillet-Saguy C, Toto A, Guerois R, Maisonneuve P, di Silvio E, Sawyer K, Gianni S, Wolff N, , Regulation of the Human Phosphatase PTPN4 by the inter-domain linker connecting the PDZ and the phosphatase domains., Sci Rep 2017 08; 7(1): 7875.
• 2017
  Amel Bahloul, Elise Pepermans, Bertrand Raynal, Nicolas Wolff, Florence Cordier, Patrick England, Sylvie Nouaille, Bruno Baron, Aziz El-Amraoui, Jean-Pierre Hardelin, Dominique Durand, Christine Petit, Conformational switch of harmonin, a submembrane scaffold protein of the hair cell mechanoelectrical transduction machinery, FEBS Letters, 2017, 591 (15), pp.2299 - 2310. ⟨10.1002/1873-3468.12729⟩.
• 2016
  Delhommel F, Wolff N, Cordier F, (1)H, (13)C and (15)N backbone resonance assignments and dynamic properties of the PDZ tandem of Whirlin, Biomol NMR Assign 2016 10;10(2):361-5.
• 2016
  Maisonneuve P, Caillet-Saguy C, Vaney MC, Bibi-Zainab E, Sawyer K, Raynal B, Haouz A, Delepierre M, Lafon M, Cordier F, Wolff N, , Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38γ., J Biol Chem 2016 08; 291(32): 16699-708.
• 2015
  Vincentelli R, Luck K, Poirson J, Polanowska J, Abdat J, Blémont M, Turchetto J, Iv F, Ricquier K, Straub ML, Forster A, Cassonnet P, Borg JP, Jacob Y, Masson M, Nominé Y, Reboul J, Wolff N, Charbonnier S, Travé G, Quantifying domain-ligand affinities and specificities by high-throughput holdup assay, Nat. Methods 2015 Aug;12(8):787-93.
• 2015
  Delhommel F, Chaffotte A, Terrien E, Raynal B, Buc H, Delepierre M, Cordier F, Wolff N, Deciphering the unconventional peptide binding to the PDZ domain of MAST2, Biochem. J. 2015 Jul;469(1):159-68.
• 2015
  Caillet-Saguy C, Maisonneuve P, Delhommel F, Terrien E, Babault N, Lafon M, Cordier F, Wolff N, , Strategies to interfere with PDZ-mediated interactions in neurons: What we can learn from the rabies virus., Prog Biophys Mol Biol 2015 Oct; 119(1): 53-9.
• 2014
  Cordier F, Chaffotte A, Wolff N, Quantitative and dynamic analysis of PTEN phosphorylation by NMR, Methods 2015 May;77-78:82-91.
• 2014
  Maisonneuve P, Caillet-Saguy C, Raynal B, Gilquin B, Chaffotte A, Pérez J, Zinn-Justin S, Delepierre M, Buc H, Cordier F, Wolff N, , Regulation of the catalytic activity of the human phosphatase PTPN4 by its PDZ domain., FEBS J 2014 Nov; 281(21): 4852-65.
• 2014
  Pulido R, Baker SJ, Barata JT, Carracedo A, Cid VJ, Chin-Sang ID, Davé V, den Hertog J, Devreotes P, Eickholt BJ, Eng C, Furnari FB, Georgescu MM, Gericke A, Hopkins B, Jiang X, Lee SR, Lösche M, Malaney P, Matias-Guiu X, Molina M, Pandolfi PP, Parsons R, Pinton P, Rivas C, Rocha RM, Rodríguez MS, Ross AH, Serrano M, Stambolic V, Stiles B, Suzuki A, Tan SS, Tonks NK, Trotman LC, Wolff N, Woscholski R, Wu H, Leslie NR, , A unified nomenclature and amino acid numbering for human PTEN., Sci Signal 2014 Jul; 7(332): pe15.
• 2014
  Caillet-Saguy C, Lim SP, Shi PY, Lescar J, Bressanelli S, , Polymerases of hepatitis C viruses and flaviviruses: structural and mechanistic insights and drug development., Antiviral Res 2014 May; 105(): 8-16.
• 2012
  Cordier F, Chaffotte A, Terrien E, Préhaud C, Theillet FX, Delepierre M, Lafon M, Buc H, Wolff N, Ordered phosphorylation events in two independent cascades of the PTEN C-tail revealed by NMR, J. Am. Chem. Soc. 2012 Dec;134(50):20533-43.
• 2012
  Terrien E, Chaffotte A, Lafage M, Khan Z, Préhaud C, Cordier F, Simenel C, Delepierre M, Buc H, Lafon M, Wolff N, Interference with the PTEN-MAST2 interaction by a viral protein leads to cellular relocalization of PTEN, Sci Signal 2012 Aug;5(237):ra58.
• 2012
  Caillet-Saguy C, Piccioli M, Turano P, Lukat-Rodgers G, Wolff N, Rodgers KR, Izadi-Pruneyre N, Delepierre M, Lecroisey A, , Role of the iron axial ligands of heme carrier HasA in heme uptake and release., J Biol Chem 2012 Aug; 287(32): 26932-43.
• 2011
  Babault N, Cordier F, Lafage M, Cockburn J, Haouz A, Prehaud C, Rey FA, Delepierre M, Buc H, Lafon M, Wolff N, Peptides targeting the PDZ domain of PTPN4 are efficient inducers of glioblastoma cell death, Structure 2011 Oct;19(10):1518-24.
• 2010
  Préhaud C, Wolff N, Terrien E, Lafage M, Mégret F, Babault N, Cordier F, Tan GS, Maitrepierre E, Ménager P, Chopy D, Hoos S, England P, Delepierre M, Schnell MJ, Buc H, Lafon M, Attenuation of rabies virulence: takeover by the cytoplasmic domain of its envelope protein, Sci Signal 2010 Jan;3(105):ra5.
• 2009
  Caillet-Saguy C, Piccioli M, Turano P, Izadi-Pruneyre N, Delepierre M, Bertini I, Lecroisey A, , Mapping the interaction between the hemophore HasA and its outer membrane receptor HasR using CRINEPT-TROSY NMR spectroscopy., J Am Chem Soc 2009 Feb; 131(5): 1736-44.
• 2009
  Terrien E, Simenel C, Prehaud C, Buc H, Delepierre M, Lafon M, Wolff N, 1H, 13C and 15N resonance assignments of the PDZ of microtubule-associated serine/threonine kinase 205 (MAST205) in complex with the C-terminal motif from the rabies virus glycoprotein, Biomol NMR Assign 2009 Jun;3(1):45-8.
• 2007
  Caillet-Saguy C, Turano P, Piccioli M, Lukat-Rodgers GS, Czjzek M, Guigliarelli B, Izadi-Pruneyre N, Rodgers KR, Delepierre M, Lecroisey A, , Deciphering the structural role of histidine 83 for heme binding in hemophore HasA., J Biol Chem 2008 Feb; 283(9): 5960-70.
• 2007
  Wolff N, Izadi-Pruneyre N, Couprie J, Habeck M, Linge J, Rieping W, Wandersman C, Nilges M, Delepierre M, Lecroisey A, Comparative analysis of structural and dynamic properties of the loaded and unloaded hemophore HasA: functional implications, J. Mol. Biol. 2008 Feb;376(2):517-25.
• 2006
  Frénal K, Callebaut I, Wecker K, Prochnicka-Chalufour A, Dendouga N, Zinn-Justin S, Delepierre M, Tomavo S, Wolff N, Structural and functional characterization of the TgDRE multidomain protein, a DNA repair enzyme from Toxoplasma gondii, Biochemistry 2006 Apr;45(15):4867-74.
• 2006
  Caillet-Saguy C, Delepierre M, Lecroisey A, Bertini I, Piccioli M, Turano P, , Direct-detected 13C NMR to investigate the iron(III) hemophore HasA., J Am Chem Soc 2006 Jan; 128(1): 150-8.
• 2004
  Frénal K, Xu CQ, Wolff N, Wecker K, Gurrola GB, Zhu SY, Chi CW, Possani LD, Tytgat J, Delepierre M, Exploring structural features of the interaction between the scorpion toxinCnErg1 and ERG K+ channels, Proteins 2004 Aug;56(2):367-75.
• 2003
  Wolff N, Sapriel G, Bodenreider C, Chaffotte A, Delepelaire P, Antifolding activity of the SecB chaperone is essential for secretion of HasA, a quickly folding ABC pathway substrate, J. Biol. Chem. 2003 Oct;278(40):38247-53.
• 2002
  Wolff N, Deniau C, Létoffé S, Simenel C, Kumar V, Stojiljkovic I, Wandersman C, Delepierre M, Lecroisey A, Histidine pK(a) shifts and changes of tautomeric states induced by the binding of gallium-protoporphyrin IX in the hemophore HasA(SM), Protein Sci. 2002 Apr;11(4):757-65.