About
A cortico-computer interface to restore speech communication
Project
SpeakOut
Language and being able to communicate is an integral part of being human. The importance of communication is perhaps most evident when it is hampered or lost, as in patients suffering from neurological or motor conditions such as locked-in syndrome (LIS), dysarthria, anarthria, amyotrophic lateral sclerosis (ALS), and aphasia.
Reconstructing intended speech from neural activity using brain-computer interfaces (BCIs) has the potential of providing a means of communication for people with severe speech production deficits. In project SpeakOut, our aim is to restore the ability to speak in those patients. We plan to develop an intracortical speech-BCI system in patients with locked-in syndrome, amyotrophic lateral sclerosis and/or cerebral palsy, who will take direct benefit from the intervention for communicating with their caregivers and relatives.
Brain-computer interfaces
A brain-computer interface (BCI) is a computer-based system that acquires and converts brain signals into outputs that communicate a user’s intent. As this communication channel does not depend on peripheral nerve and muscular activity, it can provide even paralyzed people (e.g. spinal cord injuries, strokes, ALS) with a way to express themselves. 
This project is intended for patients who have very limited or no ability to use speech. The placement of this BCI device is intended to provide direct benefit to the patient and will not be removed after the study unless it poses health risks. Aside from providing a medium for the patient to communicate, this study will also help in the development of similar systems that can restore speech for people with similar disabilities.
Team
- Anne-Lise Giraud (Institut de l’Audition)
- Emmanuel Mandonnet (Hôpital Lariboisière-ICM)
- Bertrand Thirion (INRIA Saclay)
- Soufiane Jhilal (Institut de l’Audition)
- Silvia Marchesotti (University of Geneva)
- Shizhe Wu (University of Geneva)
