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Génomes et Genetics & Microbiology Department joint seminar

VENDREDI 11 SEPTEMBRE – 11 heures 30 
Auditorium du Centre François Jacob

Contribution of phenotypic heterogeneity to bacterial adaptation.

Josep CASADESÚS

Séminaire conjoint organisé par les Départements : 
‘Génomes et Génétique’ & ‘Microbiologie’ 

Contact: Christophe Beloin (christophe.beloin@pasteur.fr) Poste 9597

 

 

Contribution of phenotypic heterogeneity to bacterial adaptation.
Josep CASADESÚS
Departamento de Genética, Universidad de Sevilla (Spain) 

Séminaire conjoint organisé par les Départements : 
‘Génomes et Génétique’ & ‘Microbiologie’ 

Abstract 
Except for bacterial species that undergo developmental programs, bacteria have been traditionally viewed as clonal populations of identical cells. In fact, bacterial genetics and physiology have routinely employed batch cultures and individual colonies assuming that all cells were identical. However, phenotypic heterogeneity is a common phenomenon in the bacterial world. In certain cases, cell-to-cell differences are merely caused by noise. In other cases, howewer, phenotypic heterogeneity reflects the formation of bacterial lineages. The mechanisms underlying lineage formation can be genetic or epigenetic. Examples of epigenetic lineage formation will be presented, and their potentially adaptive value will be discussed. 

Auditorium du Centre François Jacob – vendredi 11 septembre 2015 11:30 

Contact: Christophe Beloin (christophe.beloin@pasteur.fr)