Sarah Wong completed her PhD at the University of Hong Kong in 2014, working on the characterization of a novel antifungal small molecule against Candida species. She then joined the Unit of Cytokines and Inflammation at the Institut Pasteur for three months as a visiting intern. During this period, she studied the effect of the drug Cyclosporin A, with both immunosuppressive and antifungal activities, in murine model of invasive pulmonary aspergillosis.
In January 2016, she returned to the Institut Pasteur to join the Unit of Aspergillus as a post-doctoral fellow. Since November 2018, she is affiliated to the Unit of Molecular Mycology of the Institut Pasteur, where she is focusing on the investigation of immune interaction between human hosts and air borne fungal pathogens, Aspergillus fumigatus and Cryptococcus neoformans.
Click to view graph
Connections
Click to view timeline
Timeline
Projects
Publications
Download-
2018Fungal melanin stimulates surfactant protein D-mediated opsonization of and host immune response to spores, J. Biol. Chem. 2018 Mar;293(13):4901-4912.
-
2017Host Soluble Mediators: Defying the Immunological Inertness of Conidia, J Fungi (Basel) 2017 Dec;4(1).
-
2017Treatment of Cyclosporin A retains host defense against invasive pulmonary aspergillosis in a non-immunosuppressive murine model by preserving the myeloid cell population, Virulence 2017 11;8(8):1744-1752.
-
2016Antifungal Susceptibility in Serum and Virulence Determinants of Candida Bloodstream Isolates from Hong Kong, Front Microbiol 2016;7:216.
-
2015New “haploid biofilm model” unravels IRA2 as a novel regulator of Candida albicans biofilm formation, Sci Rep 2015 Jul;5:12433.
-
2015Antifungal susceptibility and phenotypic characterization of oral isolates of a black fungus from a nasopharyngeal carcinoma patient under radiotherapy, BMC Oral Health 2015 Mar;15:39.
-
2014In pursuit of the ideal antifungal agent for Candida infections: high-throughput screening of small molecules, Drug Discov. Today 2014 Nov;19(11):1721-1730.
-
2014In vitro and in vivo activity of a novel antifungal small molecule against Candida infections, PLoS ONE 2014;9(1):e85836.
-
2012Unraveling the resistance of microbial biofilms: has proteomics been helpful?, Proteomics 2012 Feb;12(4-5):651-65.
-
2011Antifungal susceptibility and virulence attributes of bloodstream isolates of Candida from Hong Kong and Finland, Mycopathologia 2011 Nov;172(5):389-95.
-
+View full list of publications