I am a part of the ParaFrap International PhD programme. During my PhD I will be exploring the modulations of host pathways mediated by the secreted Leishmanial kinase, CK1.
ANR Texleish: Targeting host-parasite interactions through the inhibition of excreted leishmania casein kinase 1
Leishmaniasis remains a severe public health problem, with an estimated prevalence of 12 million cases. This potentially fatal disease has a worldwide distribution and in 2012, Visceral Leishmaniasis (VL) was declared as new emerging […]
Pasteur-Weizmann project: Role of kinases in vesicle-mediated regulation of host-pathogen interactions: Focus on Leishmania donovani and Plasmodium falciparum.
The way pathogens evade the human host system is largely unknown, thus limiting our ability to cure infectious diseases. This is the case for Plasmodium, instigator of malaria, as well as Leishmania, causative agent […]
Parafrap grant : Studying two complementary infection models to identify common mechanisms of intracellular parasite survival: The roles of Leishmania and Eimeria exo-kinases in subversion of host cell signalling.
Host signalling molecules are particularly targeted by pathogens as an efficient way to interfere with multiple host pathways. Microbes evolved different strategies to hijack host cell signalling pathways: bacteria and viruses control host signalling […]
Campus France procope: CASEIN KINASE 1, A KEY REGULATOR OF TUMORIGENESIS AND HOST-PATHOGEN INTERACTIONS
Casein kinase 1 (CK1) is a family of serine/threonine protein kinases, which play essential regulatory functions in multiple cellular processes. These signalling kinases have been identified in most eukaryotes, from human to protozoa; they […]