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Projects Project ongoing 4 Members Axonal regeneration of rabies virus infected adult mouse sensory neurons Monique Lafon (PI) The virulence of a microbe is related to its capacity to invade host tissues and successfully promote its own multiplication and dissemination. Rabies virus, a neurotropic virus that causes fatal encephalitis in mammals, has […]
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Publications Download 2024 Mendia C, Peineau T, Zamani M, Felgerolle C, Yahiaoui N, Christophersen N, Papal S, Maudoux A, Maroofian R, Patni P, Nouaille S, Bowl MR, Delmaghani S, Galehdari H, Vona B, Dulon D, Vitry S, El-Amraoui A, Clarin-2 gene supplementation durably preserves hearing in a model of progressive hearing loss., Mol Ther 2024 Jan; (): . 2020 Gwenaelle G S Géléoc, Aziz El-Amraoui, Disease mechanisms and gene therapy for Usher syndrome, Hearing Research, 2020, 394, pp.107932. ⟨10.1016/j.heares.2020.107932⟩. 2020 Sedigheh Delmaghani, Aziz El-Amraoui, Inner Ear Gene Therapies Take Off: Current Promises and Future Challenges, Journal of Clinical Medicine, 2020, 9 (7), pp.2309. ⟨10.3390/jcm9072309⟩. 2020 Cherine Charfeddine, Hamza Dallali, Ghaith Abdessalem, Kais Ghedira, Yosr Hamdi, Sahar Elouej, Zied Landoulsi, Valérie Delague, Arnaud Lagarde, Nicolas Levy, Aziz El-Amraoui, Mohamed Samir Boubaker, Sonia Abdelhak, Mourad Mokni, Identification of a CDH12 potential candidate genetic variant for an autosomal dominant form of transgrediens and progrediens palmoplantar keratoderma in a Tunisian family, Journal of Human Genetics, 2020, 65 (4), pp.397 - 410. ⟨10.1038/s10038-019-0711-4⟩. 2019 Lucy A Dunbar, Pranav Patni, Carlos Aguilar, Philomena Mburu, Laura Corns, Helena Rr Wells, Sedigheh Delmaghani, Andrew Parker, Stuart Johnson, Debbie Williams, Christopher T Esapa, Michelle M Simon, Lauren Chessum, Sherylanne Newton, Joanne Dorning, Prashanthini Jeyarajan, Susan Morse, Andrea Lelli, Gemma F Codner, Thibault Peineau, Suhasini R Gopal, Kumar N Alagramam, Ronna Hertzano, Didier Dulon, Sara Wells, Frances M Williams, Christine Petit, Sally J Dawson, Steve Dm Brown, Walter Marcotti, Aziz El-Amraoui, Michael R Bowl, Clarin‐2 is essential for hearing by maintaining stereocilia integrity and function, EMBO Molecular Medicine, 2019, 11 (9), pp.e10288. ⟨10.15252/emmm.201910288⟩. 2019 Khan Z, Terrien E, Delhommel F, Lefebvre-Omar C, Bohl D, Vitry S, Bernard C, Ramirez J, Chaffotte A, Ricquier K, Vincentelli R, Buc H, Prehaud C, Wolff N, Lafon M, Structure-based optimization of a PDZ-binding motif within a viral peptide stimulates neurite outgrowth, J. Biol. Chem. 2019 Sep;294(37):13755-13768. 2019 Defourny J, Aghaie A, Perfettini I, Avan P, Delmaghani S, Petit C, , Pejvakin-mediated pexophagy protects auditory hair cells against noise-induced damage., Proc. Natl. Acad. Sci. U.S.A. 2019 04; 116(16): 8010-8017. 2018 Puy V, Darwiche W, Trudel S, Gomila C, Lony C, Puy L, Lefebvre T, Vitry S, Boullier A, Karim Z, Ausseil J, , Predominant role of microglia in brain iron retention in Sanfilippo syndrome, a pediatric neurodegenerative disease., Glia 2018 08; 66(8): 1709-1723. 2017 Menotti J, Alanio A, Sturny-Leclère A, Vitry S, Sauvage F, Barratt G, Bretagne S, , A cell impedance-based real-time in vitro assay to assess the toxicity of amphotericin B formulations., Toxicol. Appl. Pharmacol. 2017 11; 334(): 18-23. 2017 Bossou YM, Serssar Y, Allou A, Vitry S, Momas I, Seta N, Menotti J, Achard S, , Impact of Mycotoxins Secreted by Aspergillus Molds on the Inflammatory Response of Human Corneal Epithelial Cells., Toxins (Basel) 2017 06; 9(7): . + View full list of publications