Introduction of new applications
Targeted sequencing from bisulfite-converted DNA: This technology of capture allows to increase the number of studied CpG loci on the genome compared to the use of the Human Methylation 450K BeadChip. Both DNA strands […]
The capability of the MiSeq to produce paired 300-nt reads, the upgrade of its image analysis software and the dual-index sequencing strategy make it the ideal instrument for Multiplexed PCR Amplicon Sequencing.
Whole-Genome Sequencing (WGS)
This application is available at small scale on the HiSeq2500 and amplification-free DNA library preparation. For larger scale, a partnership will be established between the Institute and a Genome Centre or a commercial Company
Whole-Exome Sequencing (WES)
The Whole-Exome Sequencing is carried out on the HiSeq2500 within 4 to 5 days. The commercial capture kits of exonic regions are regularly improved. The Nextera Rapid Capture Expanded Exome delivers 62 Mb of […]
Genome-wide DNA methylation profiling
The Human Methylation 450K BeadChip enables the simultaneous quantitative monitoring of more than 480,000 CpG positions. This BeadChip has a 12-sample per array format and requiring only 500 ng of input. A positive methylated […]
Genome-wide genotyping data analysis
PFGe can support genetic linkage analysis, genome-wide association study (GWAS), and Copy Number Variation (CNV) analysis.
Mouse Genome-Wide Genotyping
The Mega Mouse Universal Genotyping array (MegaMuga), designed by a consortium, provides up to 80K SNP markers, and allows the discrimination between closely related sister strains, or between related derived strains of similar origin.s.
Human Genome-Wide Genotyping using High density SNP-microarrays
For the study of known human variants, Illumina offers a panel of BeadArrays, whose content differs from the number of markers, a few hundreds of thousands of genetic markers to 5,000,000 markers. The platform […]