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© Research
Member: Permanent Researcher

Daniel Fiole

About

 

CX3CR1 cells (green), macrophages (blue), B. anthracis spores (red). Confocal microscopy.
CX3CR1 cells (green), macrophages (blue), B. anthracis spores (red) in the lungs. Confocal microscopy performed ex vivo. Click on the image to run the animation.

Alveolar collagen (SHG, grey), CX3CR1 cells (green), B. anthracis spores (red).
Alveolar collagen (SHG, grey), CX3CR1 cells (green), B. anthracis spores (red) in the lungs. Two-photon experiment performed ex vivo. Click on the image to run the animation.

How does the body cope with sepsis?
To help answering this very broad question, I develop new imaging tools based on two-photon microscopy of the living mouse. I especially investigate in vivo the altered behavior of microglia in the brain, immune cells in the lungs and lymph nodes, and satellite cells in the muscles.

CV

APPOINTMENTS
After my PhD thesis (2010-2013) at the French Armed Forces Biomedical Research Institute, which dealt with the study of immune cells interaction in the lungs of infected mice using two-photon intravital microscopy, I worked as a postdoc at the University of California, Los Angeles (UCLA) on imaging the cortical plasticity after stroke at the cellular and functionnal level.

EDUCATION
Ph.D. in Physics for Life Sciences. University of Grenoble (France), 2013
M.Sc. in Physics. University of Grenoble (France), 2009
M.Eng. in Systems and Microsystems for Physics and Biotechnologies. Grenoble Institute of Technology (France), 2009
B.Sc. in Physics. University of Languedoc (Montpellier, France), 2006

Publications