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Antiviral Immunity, Biotherapy And Vaccines
Marie-Lise Gougeon (PI)
One of our objectives is to understand the interplay between innate and adaptive immunity in chronic viral infections, in order to identify mechanisms responsible for the lack of immune control of persistent viruses, […]
2022Defective activation and regulation of type I interferon immunity is associated with increasing COVID-19 severity., Nat Commun 2022 Nov; 13(1): 7254.
2022Enhanced TLR3 responsiveness in hepatitis C virus resistant women from the Irish anti-D cohort., Cell Rep Med 2022 Nov; 3(11): 100804.
2022Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation., Cell Rep 2022 Jun; 39(13): 110989.
2022Variability of Primary Sjögren’s Syndrome Is Driven by Interferon α and Interferon α Blood Levels Are Associated With the Class II HLA-DQ Locus., Arthritis Rheumatol 2022 Jun; (): .
2022Integrative genetic and immune cell analysis of plasma proteins in healthy donors identifies novel associations involving primary immune deficiency genes., Genome Med 2022 03; 14(1): 28.
2022Defects in mucosal immunity and nasopharyngeal dysbiosis in HSC transplanted SCID patients with IL2RG/JAK3 deficiency., Blood 2022 02; (): .
2022Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses., Front Immunol 2022 ; 13(): 897193.
2021Type I interferon response and vascular alteration in chilblain-like lesions during the COVID-19 outbreak., Br J Dermatol 2021 12; 185(6): 1176-1185.
2021Severe COVID-19 is associated with hyperactivation of the alternative complement pathway., J Allergy Clin Immunol 2021 Nov; (): .
2021Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection., Nat Immunol 2021 Sep; 22(11):1428-1439.
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