Amandine Molliex did her PhD under the supervision of J. Paul Taylor (St Jude Children’s research hospital, Memphis, USA). She studied the contribution of liquid liquid phase separation to the assembly of stress granules in the context of ALS. She then joined the laboratory of Domenico Libri (IJM, Paris) to investigate the role of Senataxin in transcription termination. She is now a post-doctoral fellow in the laboratory of Pablo Navarro (Institut Pasteur, Paris) where she studies the biophysical properties underlying transcription factors activity during mitosis.
ERC-2017-COG_BinD – Mitotic Bookmarking, Stem Cells and early Development
The goal of this project is to deliver a new theoretical framework to understand how transcription factors (TFs) sustain cell identity during developmental processes. Recognised as key drivers of cell fate acquisition, TFs are […]
Inheritance of the pluripotency network’s activity
The preservation of pluripotency throughout cell division – self-renewal -, is strictly dependent on the highly efficient action of the pluripotency gene regulatory network. However, how TFs cope with replication and mitosis, two major […]