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© Uwe Maskos
Tranche d'hippocampe de souris colorée avec deux toxines spécifiques de sous-types de récepteur nicotinique, en rouge (grains), et en vert (corps cellulaires). L'hippocampe est la zone du cerveau qui gère la mémoire spatiale.
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Application Deadline
02
Oct 2017
2017-10-02 8:00:00 2017-10-02 18:00:00 Europe/Paris We are looking for postdoc candidates to study addiction-like processes in rat models Our lab Integrative Neurobiology of Cholinergic System investigates, through combined approaches from molecular and cellular biology to behavioral and cognitive neuroscience, the role of nicotinic acetylcholine receptors (nAChRs) in a set of neurobiological functions, […] "25-28 rue du Dr. Roux, 75015, Paris" Uwe Maskos uwe.maskos@pasteur.fr

Our lab Integrative Neurobiology of Cholinergic System investigates, through combined approaches from molecular and cellular biology to behavioral and cognitive neuroscience, the role of nicotinic acetylcholine receptors (nAChRs) in a set of neurobiological functions, notably in the context of neurodegenerative and psychiatric diseases.

We are currently studying the contribution of nAChRs to addiction-like processes, using drug self-administration procedures in transgenic rats that we have recently generated in the lab. We now aim at pursuing our projects by combining the use of DREADD technology and touch-screen cognitive testing to these approaches, in order to further decipher the mechanisms underlying cholinergic modulation of processes implicated in addiction, as well as in addiction and schizophrenia co-morbidity.

In this context, we are looking for postdoc candidates for grant applications, with significant expertise in rat behavioral testing, DREADD technology and/or touchscreen cognitive testing.

Please contact Morgane Besson. email : morgane.besson@pasteur.fr