Search anything and hit enter
  • Teams
  • Members
  • Projects
  • Events
  • Calls
  • Jobs
  • publications
  • Software
  • Tools
  • Network
  • Equipment

A little guide for advanced search:

  • Tip 1. You can use quotes "" to search for an exact expression.
    Example: "cell division"
  • Tip 2. You can use + symbol to restrict results containing all words.
    Example: +cell +stem
  • Tip 3. You can use + and - symbols to force inclusion or exclusion of specific words.
    Example: +cell -stem
e.g. searching for members in projects tagged cancer
Search for
Count
IN
OUT
Content 1
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Clinical Research Nurse
  • Clinician Researcher
  • Department Manager
  • Dual-education Student
  • Full Professor
  • Honorary Professor
  • Lab assistant
  • Master Student
  • Non-permanent Researcher
  • Nursing Staff
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Prize
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Content 2
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Clinical Research Nurse
  • Clinician Researcher
  • Department Manager
  • Dual-education Student
  • Full Professor
  • Honorary Professor
  • Lab assistant
  • Master Student
  • Non-permanent Researcher
  • Nursing Staff
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Prize
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Search

← Go to Research

Go back
Scroll to top
Share
© Research
Job

Post-doc position on Molecular Mechanisms of Accelerated and Physiological Ageing, including in cerebral organoids – Institut Pasteur, Paris

Scientific Fields
Diseases
Organisms
Applications
Technique
Application Deadline
16
Oct 2023
2023-10-16 8:00:00 2023-10-16 18:00:00 Europe/Paris Post-doc position on Molecular Mechanisms of Accelerated and Physiological Ageing, including in cerebral organoids – Institut Pasteur, Paris A post-doc position is available at Institut Pasteur, Paris, in the lab of M. Ricchetti to study themolecular mechanisms underlying a progeroid disease, Cockayne syndrome, and their link with regular ageing. A particular attention […] "25-28 rue du Dr. Roux, 75015, Paris" Miria Ricchetti miria.ricchetti@pasteur.fr


A post-doc position is available at Institut Pasteur, Paris, in the lab of M. Ricchetti to study the
molecular mechanisms underlying a progeroid disease, Cockayne syndrome, and their link with regular ageing. A particular attention is given to ageing-related degenerative processes using patient-derived iPSCs and cerebral organoids as a model. The investigation may include – omics analyses, the role of mitochondrial dysfunction and oxidative stress in accelerated as well as physiological ageing. Most studies are done with patient-derived material. A novel mouse model is also used.

Our study is based on a novel and experimentally supported hypothesis linking transcriptional
changes, largely resulting from epigenomic regulation, in turn depending on the management of oxidative and nitrosative stress, as triggers of ageing-related degenerative processes. These studies have implication for therapeutic perspectives. We also aim to discover and functionally validate novel genes involved in the ageing process.


Experience in ageing-related studies is strongly recommended. The candidate should have an
experimental background in at least one of the following fields: iPSCs and cerebral organoids
cultures, cellular biology, confocal microscopy, omics analysis (DNA methylation and RNAseq),
CRISPR/Cas9 technology.
Large intellectual autonomy and experimental excellence are required.

Funds are available for one year, with possibility of prolongation.
The position is available immediately.

Send motivation letter, CV with list of publications, and reference letters to
miria.ricchetti@pasteur.fr

Chatre et al, 2015, Proc. Natl, Acad Sci USA, PMID: 26038566
Crochemore et al, 2019, Nature Communications, PMID: 31811121
Crochemore et al, 2022, Antioxidt Redox Signal, PMID: 34428933
Crochemore et al, 2023, Aging Cell, in press

Miria Ricchetti, Ph.D.
Molecular Mechanisms of Pathological and Physiological Ageing
Dept. of Developmental & Stem Cell Biology, Institut Pasteur
CNRS UMR3738
25 rue du Dr. Roux, 75015, Paris, France
Office: +33 (1) 4568 8567; miria.ricchetti@pasteur.fr