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© Research
Job

2 (+1)-years Post-Doc position : Carmen Buchrieser’s lab “Biology of Intracellular Bacteria”, Department of Microbiology, Institut Pasteur, Paris

Scientific Fields
Diseases
Organisms
Applications
Technique
Application Deadline
30
Jan 2022
2022-01-30 8:00:00 2022-01-30 18:00:00 Europe/Paris 2 (+1)-years Post-Doc position : Carmen Buchrieser’s lab “Biology of Intracellular Bacteria”, Department of Microbiology, Institut Pasteur, Paris Characterising the structure and content of extracellular vesicles derived from Legionella pneumophila and human cells The Project A postdoctoral position is available at the Institut Pasteur in Paris to analyse the structure and content […] "25-28 rue du Dr. Roux, 75015, Paris"

Characterising the structure and content of extracellular vesicles derived from Legionella pneumophila and human cells

The Project

A postdoctoral position is available at the Institut Pasteur in Paris to analyse the structure and content of extracellular vesicles shed by Legionella pneumophila (Lp-EVs) in vitro and in cellulo.

Our lab at the Institut Pasteur has recently shown that Legionella pneumophila sheds membrane vesicles that transport cargo such as proteins and RNAs in the host cell that helps to achieve better intracellular replication of L. pneumophila. In the here proposed project we have joined forces with the group of G. Lavieu to:

1) characterize this transport at the cellular and molecular levels

2) and to identify the core machinery responsible for L. pneumophila– derived EV delivery.

As part of this project, we search for a postdoc who will employ Cryo EM of and cryo-CLEM of Lp-EVs and hEVs to analyse their structure and cargo.

Where? 

The project will be carried out in the Biology of Intracellular Bacteria lab expert in biology of Legionella and the analyses of extracellular vesicles and the Nanoimaging Core facility at the Institut Pasteur and in close collaboration with the group of G. Lavieu at the Université de Paris , expert of human extracellular vesicles (exosomes) (hEvs).

Profile

Applicants must hold a PhD in a relevant field. Prior experience with CryoEM is expected. Technical proficiency in molecular and cellular biology and work with bacterial pathogens would be a significant advantage. High motivation, excellent communication skills, and ability to work collaboratively in a team and with other teams are essential.

To apply please send a single pdf file to cbuch@pasteur.fr containing (1) a cover letter outlining your previous experiences that make you suitable for this position as well as your research, training and career goals, (2) your CV (3) contact information for 3 references

How to apply ?

To apply please send a single pdf file to cbuch@pasteur.fr containing (1) a cover letter outlining your previous experiences that make you suitable for this position as well as your research, training and career goals, (2) your CV (3) contact information for 3 references

The position is available immediately and will remain open until filled. The expected start date is early 2022. The position is initially for 2 years with a one-year renewal possibility.