Search anything and hit enter
  • Teams
  • Members
  • Projects
  • Events
  • Calls
  • Jobs
  • publications
  • Software
  • Tools
  • Network
  • Equipment

A little guide for advanced search:

  • Tip 1. You can use quotes "" to search for an exact expression.
    Example: "cell division"
  • Tip 2. You can use + symbol to restrict results containing all words.
    Example: +cell +stem
  • Tip 3. You can use + and - symbols to force inclusion or exclusion of specific words.
    Example: +cell -stem
e.g. searching for members in projects tagged cancer
Search for
Count
IN
OUT
Content 1
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Full Professor
  • Graduate Student
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Content 2
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Full Professor
  • Graduate Student
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Search
Go back
Scroll to top
Share
© Research
Event

“Trans-splicing and RNA modification regulate the life and death of Trypanosoma brucei”

Scientific Fields
Diseases
Organisms
Applications
Technique
Date
07
Jan 2016
Time
12:00:00
Institut Pasteur, Rue du Docteur Roux, Paris, France
Address
Building: Lwoff Room: Retrovirus
Location
2016-01-07 12:00:00 2016-01-07 13:00:00 Europe/Paris “Trans-splicing and RNA modification regulate the life and death of Trypanosoma brucei” Shulamit MICHAELI – Bar Ilan University (Ramat Gan – Israel) In the seminar I will report on the discovery and the mechanism of the spliced leader silencing (SLS) pathway which is induced under ER […] Institut Pasteur, Rue du Docteur Roux, Paris, France Gérald Spaeth gerald.spaeth@pasteur.fr

About

ShulaMichaeli.jpgShulamit MICHAELI – Bar Ilan University (Ramat Gan – Israel)

In the seminar I will report on the discovery and the mechanism of the spliced leader silencing (SLS) pathway which is induced under ER stress, and pH stress.   The mechanism involves the shut-off of SL RNA transcription and the induction programmed cell death; then I will describe how perturbation in SL RNA biogenesis leads to the transport of the RNA to the cytoplasm and its final excretion by exosomes which affects social motility. In the last part of my talk I will describe our work on the regulation of small nucleolar RNAs which guide RNA modification and its possible importance for adaptation of the parasite to living in the mammalian host.

Contact : Gerald Spaeth (gerald.spaeth@pasteur.fr – Poste 38.58)

Location

Building: Lwoff
Room: Retrovirus
Address: Institut Pasteur, Rue du Docteur Roux, Paris, France