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“Pre-mortem and post-mortem research on life-threatening paediatric infections”

Dr Gregory MOSELEY – Infection & Epidemiology Seminar

© Institut Pasteur/Marco Gualtieri & Pauline Spéder

Event

SEMINAR ” Stem cells, diet, and physiology” by Professor Daniela Drummond-Barbosa

Department of: Developmental and Stem Cell Biology

Member: François Schweisguth

Scientific Fields

Diseases

Organisms

Applications

Technique

Date

28

Apr 2017

Time

12:00:00

25 Rue du Docteur Roux, Paris, France

Address

Building: J.Monod (#66)

Location

2017-04-28 12:00:00 2017-04-28 13:15:00 Europe/Paris SEMINAR ” Stem cells, diet, and physiology” by Professor Daniela Drummond-Barbosa Department of Developmental and Stem Cell Biology 2017 Seminar Series Friday 28th April— at 12.00 pm @ Amphi Jacques Monod (Bât.66) SEMINAR “Stem cells, diet, and physiology” Invited Speaker ⇒ Daniela Drummond-Barbosa Department of […] 25 Rue du Docteur Roux, Paris, France François Schweisguth francois.schweisguth@pasteur.fr

About

Department of Developmental and Stem Cell Biology

2017 Seminar Series

Friday 28th April— at 12.00 pm @ Amphi Jacques Monod (Bât.66)

SEMINAR “Stem cells, diet, and physiology”

Invited Speaker ⇒ Daniela Drummond-Barbosa

Department of Biochemistry and Molecular Biology, John Hopkins University – Baltimore, USA

Abstract : Nutrient availability influences tissue stem cell lineages in a wide range of multicellular organisms. Dr. Drummond-Barbosa pioneered using Drosophila melanogaster as a model to study adult tissue stem cell regulation by diet, and her laboratory identified several mechanisms involving insulin-like peptides, the steroid hormone ecdysone, the nutrient sensor Target of Rapamycin (TOR), and other diet-regulated pathways that modulate germline stem cells (GSCs) and their differentiating progeny. More recently, Dr. Drummond-Barbosa’s lab discovered that adipocyte-specific disruption of amino acid transport, TOR or insulin signaling causes distinct GSC lineage phenotypes, and that diet controls multiple metabolic pathways within adipocytes that can influence specific processes in the GSC lineage. These results point to extensive communication between adipocytes and the ovary, and underscore the complexity of the physiological network that is integrated with intrinsic and local factors to modulate stem cell behavior according to dietary constraints.

Hosted by François Schweisguth

Location

Building: J.Monod (#66)
Address: 25 Rue du Docteur Roux, Paris, France

Published on: 31 Mar 2017

(function($) { /* * render_map * * This function will render a Google Map onto the selected jQuery element * * @type function * @date 8/11/2013 * @since 4.3.0 * * @param $el (jQuery element) * @return n/a */ function render_map( $el ) { var MY_MAPTYPE_ID = 'custom_style'; var featureOpts = [{"stylers":[{"hue":"#0088ff"}]}]; var styledMapOptions = { name: 'Custom Style' }; var customMapType = new google.maps.StyledMapType(featureOpts, styledMapOptions); // var var $markers = $el.find('.marker'); // vars var args = { zoom : 16, scrollwheel : false, center : new google.maps.LatLng(0, 0), mapTypeId : google.maps.MapTypeId.ROADMAP, mapTypeId : MY_MAPTYPE_ID }; // create map var map = new google.maps.Map( $el[0], args); map.mapTypes.set(MY_MAPTYPE_ID, customMapType); // add a markers reference map.markers = []; // add markers $markers.each(function(){ add_marker( $(this), map ); }); // center map center_map( map ); } /* * add_marker * * This function will add a marker to the selected Google Map * * @type function * @date 8/11/2013 * @since 4.3.0 * * @param $marker (jQuery element) * @param map (Google Map object) * @return n/a */ function add_marker( $marker, map ) { // var var latlng = new google.maps.LatLng( $marker.attr('data-lat'), $marker.attr('data-lng') ); //var image = 'https://research.pasteur.fr/wp-content/themes/biologyx2/images/logomap.png'; var myIcon = new google.maps.MarkerImage('https://research.pasteur.fr/wp-content/themes/biologyx2/images/map-pin.png', null, null, null, new google.maps.Size(32,32)); // create marker var marker = new google.maps.Marker({ position : latlng, map : map, icon : myIcon }); // add to array map.markers.push( marker ); // if marker contains HTML, add it to an infoWindow if( $marker.html() ) { // create info window var infowindow = new google.maps.InfoWindow({ content : $marker.html() }); // show info window when marker is clicked google.maps.event.addListener(marker, 'click', function() { infowindow.open( map, marker ); }); } } /* * center_map * * This function will center the map, showing all markers attached to this map * * @type function * @date 8/11/2013 * @since 4.3.0 * * @param map (Google Map object) * @return n/a */ function center_map( map ) { // vars var bounds = new google.maps.LatLngBounds(); // loop through all markers and create bounds $.each( map.markers, function( i, marker ){ var latlng = new google.maps.LatLng( marker.position.lat(), marker.position.lng() ); bounds.extend( latlng ); }); // only 1 marker? if( map.markers.length == 1 ) { // set center of map map.setCenter( bounds.getCenter() ); map.setZoom( 15 ); } else { // fit to bounds map.fitBounds( bounds ); } } /* * document ready * * This function will render each map when the document is ready (page has loaded) * * @type function * @date 8/11/2013 * @since 5.0.0 * * @param n/a * @return n/a */ $(document).ready(function(){ $('.acf-map').each(function(){ render_map( $(this) ); }); }); })(jQuery);