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Scientific Fields
Diseases
Organisms
Applications
Technique
Date
17
Dec 2018
Time
10:00:00
28 Rue du Docteur Roux, Paris, France
Address
Building: François Jacob Room: Auditorium
Location
2018-12-17 10:00:00 2018-12-17 00:00:00 Europe/Paris Seminar “Maternal Microbiome and its Role in Infant Health Abstract : Recent reports suggest that early microbial colonization has an important role for in promoting health. This may contribute to reduce the risk of chronic diseases such as obesity, allergies and inflammatory conditions. […] 28 Rue du Docteur Roux, Paris, France Philippe Sansonetti philippe.sansonetti@pasteur.fr

Speakers

Maria Carmen COLLADO
(Centro Superior de Investigaciones Cientificas CSIC, Valencia, Spain)

About

Abstract :

Recent reports suggest that early microbial colonization has an important role for in promoting health. This may contribute to reduce the risk of chronic diseases such as obesity, allergies and inflammatory conditions. Advances in understanding host-microbe interactions imply that maternal microbiota plays a crucial role on health programming. This process begins in utero and it is modulated by mode of delivery and diet. Research has shown that i) specific shifts in milk microbial composition are associated with lactation time and mode of delivery, ii) milk microbes drive the infant microbiota composition; iii) maternal microbiota dysbiosis may be transferred to the infant. However, factors defining maternal microbiota and its biological role upon infant’s health are not yet fully understood. Hence, it is imporant to characterize maternal microbes to be transferred to neonates and determine their function in infant health programming. The specific aims of her present research focus are:(1) understanding how the maternal microbiome is influenced by host and environmental factors;(2) characterizing the microbial core and bioactive compounds transmitted to the offspring mainly via breastfeeding and their key roles in the microbial modulation and host response;(3) understanding the interactions among breast milk bioactive compounds and their role in infant health;(4) shedding light on how maternal microbes influence the infant immune system & (5)development of new dietary strategies and therapies based on microbial replacement and modulation. Results presented will focus on the interaction between infant nutrition, microbes and host response in early life and its key role in health programming, enabling new applications in the field of personalized nutrition & medicine.

Location

Building: François Jacob
Room: Auditorium
Address: 28 Rue du Docteur Roux, Paris, France