Search anything and hit enter
  • Teams
  • Members
  • Projects
  • Events
  • Calls
  • Jobs
  • publications
  • Software
  • Tools
  • Network
  • Equipment

A little guide for advanced search:

  • Tip 1. You can use quotes "" to search for an exact expression.
    Example: "cell division"
  • Tip 2. You can use + symbol to restrict results containing all words.
    Example: +cell +stem
  • Tip 3. You can use + and - symbols to force inclusion or exclusion of specific words.
    Example: +cell -stem
e.g. searching for members in projects tagged cancer
Search for
Count
IN
OUT
Content 1
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Clinical Research Nurse
  • Clinician Researcher
  • Department Manager
  • Dual-education Student
  • Full Professor
  • Honorary Professor
  • Lab assistant
  • Master Student
  • Non-permanent Researcher
  • Nursing Staff
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Prize
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Content 2
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Clinical Research Nurse
  • Clinician Researcher
  • Department Manager
  • Dual-education Student
  • Full Professor
  • Honorary Professor
  • Lab assistant
  • Master Student
  • Non-permanent Researcher
  • Nursing Staff
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Prize
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Search
Go back
Scroll to top
Share
© Research
Event

“Statistical design and analysis of reproducible quantitative mass spectrometry-based experiments” – C3BI Seminar-Retrovirus Room (Lwoff)

Scientific Fields
Diseases
Organisms
Applications
Technique
Date
07
Dec 2017
Time
14:00:00
Institut Pasteur, Paris, France
Address
Building: Lwoff
Location
2017-12-07 14:00:00 2017-12-07 15:00:00 Europe/Paris “Statistical design and analysis of reproducible quantitative mass spectrometry-based experiments” – C3BI Seminar-Retrovirus Room (Lwoff) Statistical methodology is key for quantitative proteomics, as it helps reduce bias and inefficiencies, distinguish the systematic variation from random artifacts, and maximize the reproducibility of the results. This talk will overview the statistical […] Institut Pasteur, Paris, France

About

Statistical methodology is key for quantitative proteomics, as it helps reduce bias and inefficiencies, distinguish the systematic variation from random artifacts, and maximize the reproducibility of the results. This talk will overview the statistical methodology implemented in MSstats, an open-source R package for statistical relative quantification of proteins and peptides. MSstats supports experiments with complex designs, such as comparisons of multiple groups or time course comparisons. It handles quantitative shotgun DDA (data-dependent acquisition) experiments, targeted SRM (selected reaction monitoring), and SWATH/DIA (data independent acquisition) experiments. It can be used in conjunction with label-free experimental workflows, or with workflows that utilize stable isotope reference proteins or peptides. MSstats contains functionalities for data processing, model-based statistical analysis (including testing proteins and peptides for differential abundance, or estimating protein abundance on a relative scale), and model-based calculation of a sample size for a future experiment. It also contains functionalities for systems suitability and statistical process control, and for quantification of figures of merit (such as limit of detection) of mass spectrometric assays. MSstats is available stand-alone or via graphical user interface as an external tool in the software framework Skyline. It can be interfaced with numerous spectral processing tools, such as MaxQuant.

Location

Building: Lwoff
Address: Institut Pasteur, Paris, France