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© Research
Event

“Mechanisms of selective translation stimulation and suppression by the multiple eIF4E isoforms of Trypanosoma brucei” – Christine Clayton

Scientific Fields
Diseases
Organisms
Applications
Technique
Date
26
Mar 2020
Time
12:00:00
25-28 Rue du Dr Roux, 75015 Paris, France
Address
Building: Lwoff Room: Retrovirus
Location
2020-03-26 12:00:00 2020-03-26 13:00:00 Europe/Paris “Mechanisms of selective translation stimulation and suppression by the multiple eIF4E isoforms of Trypanosoma brucei” – Christine Clayton Christine Clayton – Centre for Molecular Biology of Heidelberg University (ZMBH), Germany Trypanosoma brucei has six isoforms of the cap-binding translation initiation factor eIF4E, and five eIF4Gs. I will focus on mechanisms by which […] 25-28 Rue du Dr Roux, 75015 Paris, France Gérald Spaeth gerald.spaeth@pasteur.fr

About

Christine Clayton – Centre for Molecular Biology of Heidelberg University (ZMBH), Germany

Trypanosoma brucei has six isoforms of the cap-binding translation initiation factor eIF4E, and five eIF4Gs. I will focus on mechanisms by which the different complexes suppress or promote translation initiation. I will also discuss the links between translation initiation, the stimulatory MKT-PBP1 complex, and expression of developmentally regulated surface proteins including the variant surface glycoprotein that is responsible for antigenic variation.

website : https://www.zmbh.uni-heidelberg.de/clayton/default.shtml

 

Location

Building: Lwoff
Room: Retrovirus
Address: 25-28 Rue du Dr Roux, 75015 Paris, France