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© Research
Event

“Doing things differently: the evolution of Bordetella pertussis” Genomes and Genetics with Global Health Departments seminar

Scientific Fields
Diseases
Organisms
Applications
Technique
Date
13
Feb 2020
Time
11:00:00
25-28 Rue du Dr Roux, 75015 Paris, France
Address
Building: rdc Centre François Jacob Room: auditorium du CFJ
Location
2020-02-13 11:00:00 2020-02-13 12:30:00 Europe/Paris “Doing things differently: the evolution of Bordetella pertussis” Genomes and Genetics with Global Health Departments seminar Abstract: Most studies of bacterial genetic diversity have focused on the metrics of SNPs and gene content. However, other types of genetic diversity exist, but are poorly studied, including genome arrangement and copy number […] 25-28 Rue du Dr Roux, 75015 Paris, France Sylvain Brisse sylvain.brisse@pasteur.fr

About

Abstract:

Most studies of bacterial genetic diversity have focused on the metrics of SNPs and gene content. However, other types of genetic diversity exist, but are poorly studied, including genome arrangement and copy number variations. The application of long-read sequencing to the study of B. pertussis reveals that variation in genome structure dominates the genetic diversity of this species, providing a unique opportunity to understand its role in generating phenotypic diversity, and thus in driving evolution and adaptation of this re-emerging pathogen.

Location

Building: rdc Centre François Jacob
Room: auditorium du CFJ
Address: 25-28 Rue du Dr Roux, 75015 Paris, France