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© Research
Event

Department Seminar by Renata Basto, Institut Curie: “Genetic instability in development and disease”

Scientific Fields
Diseases
Organisms
Applications
Technique
Date
09
Feb 2018
Time
11:00:00
25 Rue du Dr Roux, Paris, France
Address
Building: Monod Room: Amphi Monod
Location
2018-02-09 11:00:00 2018-02-09 12:00:00 Europe/Paris Department Seminar by Renata Basto, Institut Curie: “Genetic instability in development and disease” Renata Basto – Biology of centrosomes and genetic instability lab, UMR144, Institut Curie, Paris, France Abstract: The processes that contribute to maintaining a stable (euploid) genome content in multicellular organisms are of vital importance. They […] 25 Rue du Dr Roux, Paris, France Pauline Speder pauline.speder@pasteur.fr

About

Renata Basto – Biology of centrosomes and genetic instability lab, UMR144, Institut Curie, Paris, France

Abstract: The processes that contribute to maintaining a stable (euploid) genome content in multicellular organisms are of vital importance. They ensure viability of stem and progenitor cells by contributing to their fitness and performance during both development and adulthood. In the germline, genome stability ensures the transmission of species-specific traits across generations. However, variations to the normal euploid genome content are frequently found in healthy animals and are thought to contribute with phenotypic variability in adverse situations. Yet they are also at the basis of several human diseases, including neuro-developmental disorders and cancer. In this talk I will discuss how tissue respond to variations in in whole chromosome number and their impact on organism homeostasis.

 

Location

Building: Monod
Room: Amphi Monod
Address: 25 Rue du Dr Roux, Paris, France