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© Romain Levayer, Institut Pasteur
Epithelial layer of the Drosophila pupal thorax (notum). White : cell contour (E-cadherin), pseudocolour : Dpp sensor.
Event

Cell death and epithelial homeostasis unit seminar: « Using microfluidics for quantitative studies of post-embryonic development in C. elegans», by Wolfgang Keil, Physico-Chemistry department, Institut Curie

Scientific Fields
Diseases
Organisms
Applications
Technique
Date
28
May 2019
Time
14:00:00
25 Rue du Docteur Roux, Paris, France
Address
Building: Monod building (#66)
Location
2019-05-28 14:00:00 2019-05-28 15:00:00 Europe/Paris Cell death and epithelial homeostasis unit seminar: « Using microfluidics for quantitative studies of post-embryonic development in C. elegans», by Wolfgang Keil, Physico-Chemistry department, Institut Curie Tuesday, May 28th, at 2:00 pm Monod amphitheater, Monod building « Using microfluidics for quantitative studies of post-embryonic development in C. elegans» Wolfgang Keil Physico-Chemistry department, Institut Curie   Abstract: The development of most metazoans can […] 25 Rue du Docteur Roux, Paris, France Romain Levayer romain.levayer@pasteur.fr

About

Tuesday, May 28th, at 2:00 pm
Monod amphitheater, Monod building

« Using microfluidics for quantitative studies of post-embryonic development in C. elegans»

Wolfgang Keil
Physico-Chemistry department, Institut Curie

 

Abstract: The development of most metazoans can be divided in an early phase of embryogenesis and a subsequent phase of post-embryonic development. Developmental dynamics during the post-embryonic phase are generally much slower and often controlled by very different molecular mechanisms that, e.g., ensure tissue synchrony and integrate metabolic queues. However, obtaining long-term in-vivo quantitative imaging data post-embryonically with good statistical and cellular resolution has been highly challenging because animals must be allowed to grow, feed, and move in order to properly develop after embryogenesis. In this talk, I will discuss our recent progress in overcoming these challenges in the model organism C. elegans, using microfluidics technology. I will then outline two of our studies, in which quantitative in-vivo imaging data of post-embryonic development allows novel insights into mechanisms of cell-fate acquisition and the regulation of oscillatory gene expression in C. elegans.

Hosted by Romain Levayer
romain.levayer@pasteur.fr

Location

Building: Monod building (#66)
Address: 25 Rue du Docteur Roux, Paris, France