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© Matteo Bonazzi, Edith Gouin
Observation en immunofluorescence d'une cellule infectée par Listeria monocytogenes. En bleu: marquage des protéines de surface de Listeria qui permet de visualiser les bactéries. En rouge et vert: marquage de l'actine, une protéine qui forme le cytosquelette des cellules. Les Listeria utilisent l'actine cellulaire pour former des "comêtes" et se déplacer à l'intérieur des cellules qu'elles infectent. Cell infected by Listeria monocytogenes. The surface proteins (in blue) of Listeria enable us to view the bacteria. Actin, a constituent protein of cells, is shown in red and green.
Event

Antibodies as Drugs 2021 (Keystone Symposia)

Scientific Fields
Diseases
Organisms
Applications
Technique
Starting Date
27
Jan 2021
Ending Date
30
Jan 2021
Time
08:00:00
Whistler, BC V0N, Canada
Address
2021-01-27 08:00:00 2021-01-30 19:00:00 Europe/Paris Antibodies as Drugs 2021 (Keystone Symposia) Antibodies as Drugs Scientific Organizers: Pierre Bruhns, Patrick C. Wilson, Esther Breij and David P. Humphreys Date: January 27 – 30, 2021 Location: Fairmont Chateau Whistler, Whistler, BC, Canada https://www.keystonesymposia.org/KS/Online/Events/2021A6/Details.aspx?EventKey=2021A6 Therapeutic antibodies largely populate […] Whistler, BC V0N, Canada Pierre Bruhns pierre.bruhns@pasteur.fr

About

Scientific Organizers: Pierre Bruhns, Patrick C. Wilson, Esther Breij and David P. Humphreys
Date: January 27 – 30, 2021
Location: Fairmont Chateau Whistler, Whistler, BC, Canada

Therapeutic antibodies largely populate the list of top biologic drugs since years. They revolutionize the treatment of pathologies falling into major disease areas, including cancer, chronic inflammatory diseases, allergy and infectious diseases. More and more antibodies are being proposed to treat an expanding number of pathologies, but in parallel more and more resistance/escape mechanisms are described, forcing academia and industry to search for alternative concepts to prevent unresponsiveness or treat resistant patients. Not only methodological and technological advances, but also paradigm-shifting concepts are developed to face these challenges. This Keystone Symposia conference aims to present the state-of-the-art in antibody therapeutics, repertoires & deep learning, bispecific antibodies and engineering from industry and academia. Specifically, we wish to highlight and discuss recent breakthroughs in identifying therapeutics from volunteers/patients, understanding vaccination and mode of delivery, modalities for half-life extensions and involvement of complement in the antibodies mode of action. We think this upcoming period will showcase the rise of bispecifics in the therapeutic landscape and propose to highlight the technologies to develop them, their functionalities, and clinical efficacies, particularly in immune-oncology.

Registration opens in January 2020

Location

Address: Whistler, BC V0N, Canada