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© Research
Publication : Trends in microbiology

Spotlight on FtsZ-based cell division in Archaea.

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Trends in microbiology - 01 Jul 2022

Ithurbide S, Gribaldo S, Albers SV, Pende N

Link to Pubmed [PMID] – 35246355

Link to DOI – 10.1016/j.tim.2022.01.005

Trends Microbiol 2022 Jul; 30(7): 665-678

Compared with the extensive knowledge on cell division in model eukaryotes and bacteria, little is known about how archaea divide. Interestingly, both endosomal sorting complex required for transport (ESCRT)-based and FtsZ-based cell division systems are found in members of the Archaea. In the past couple of years, several studies have started to shed light on FtsZ-based cell division processes in members of the Euryarchaeota. In this review we highlight recent findings in this emerging field of research. We present current knowledge of the cell division machinery of halophiles which relies on two FtsZ proteins, and we compare it with that of methanobacteria, which relies on only one FtsZ. Finally, we discuss how these differences relate to the distinct cell envelopes of these two archaeal model systems.