POST-DOCTORAL POSITION IN MOLECULAR AND CELLULAR BIOLOGY
to study GPCR’s conformational arrangement
Job description
The postdoctoral position is available in Anne Brelot’s group in the Dynamics of Host-Pathogen Interaction Unit directed by Jost Enninga (Institut Pasteur, Paris). Anne Brelot‘s research focuses on the dissection of G protein-coupled receptors (GPCR) function and intracellular trafficking, with an emphasis on the chemoreceptors. These receptors, involved in the migration of immune cells, have been implicated in the physiopathology of several diseases, including viral infections, metabolic diseases, neurodegeneration, and cancer progression.
The candidate will work on an interdisciplinary project that aims to study the dimerization of two chemokine receptors using biochemistry, biophysics, cell biology, and live cell imaging. These studies will provide a better understanding of the diversity and dynamics of chemokine receptor populations at the cell surface with the goal to develop molecules targeting a specific state of the receptors.
Your qualification
The successful candidate should have a doctoral degree in biology and documented experience in biochemistry, cell biology, real-time microscopy, and biophysics. A background in the molecular pharmacology of G protein-coupled receptors would be advantageous. The candidate should be able to interact with members of an interdisciplinary partnership of cell biologists, computer scientists, and inflammation experts, and possess excellent interpersonal and scientific communication skills.
Our Offer
Our unit is part of the Cell Biology and Infection department. We work in a dynamic and international team with a strong sense of collaboration.
The full-time position is available starting in October 2022. It is funded by the French National Research Agency (ANR) for 2 years. Salary and social benefits will be in accordance with the regulations of the Pasteur Institut.
To apply, please send your complete application to anne.brelot@pasteur.fr including a cover letter, a curriculum vitae, and the names of three references.