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  • Undergraduate Student
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  • Deputy Director of National Reference Center
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  • Director of Center
  • Director of Department
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© Structural Dynamics Of Macromolecules
The structure of a bacterial analog of the nicotinic receptor (one color per subunit) inserted into the cell membrane (grey and orange). A representation of the volume accessible to ions is shown in yellow.
Scientific Fields
Diseases
Organisms
Applications
Technique

Projects

Project
Ongoing
7 Members

DNA-binding mechanism and evolution of replication protein A

Ludovic Sauguet (PI)

Replication Protein A (RPA) is a heterotrimeric single stranded DNA-binding protein with essential roles in DNA replication, recombination and repair. Little is known about the structure of RPA in Archaea, the third domain of […]
Project
Ongoing
4 Members

STRUCTURAL BASIS FOR DNA REPLICATION AND REPLICATION-COUPLED DNA REPAIR IN ARCHAEA

Ludovic Sauguet (PI)

One fundamental challenge of cells is to accurately copy their genetic material for cell proliferation. DNA replication is performed by sophisticated multi-protein machines, which must synthesize DNA continuously and copy it accurately at the […]

Publications

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