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© Institut Pasteur
Spirochète : bactérie hélicoïdale, flexible et ondulante de longueur variable, non colorable par la coloration de Gram, très mobile (endoflagelles). Trois familles : Spirochaetaceae, Leptospiraceae, et Brachyspiraceae. Principaux genres pathogènes pour l'homme : Borrelia (Borrelia burgdorferi cause de la maladie de Lyme), Treponema (Treponema pallidum cause de la syphillis), Leptospira (Leptospira interrogans serovar icterohaemorrhagiae cause de la maladie de Weil). Image colorisée.
Publication : Emerging infectious diseases

Factors Associated with Severe Leptospirosis, Martinique, 2010-2013

Team: Biology of Spirochetes
Reference Center: Leptospirosis
Member: Mathieu Picardeau
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Emerging infectious diseases - 01 Dec 2015

Hochedez P, Theodose R, Olive C, Bourhy P, Hurtrel G, Vignier N, Mehdaoui H, Valentino R, Martinez R, Delord JM, Herrmann C, Lamaury I, Césaire R, Picardeau M, Cabié A

Link to Pubmed [PMID] – 26583702

Emerging Infect. Dis. 2015 Dec;21(12):2221-4

To identify factors associated with disease severity, we examined 102 patients with quantitative PCR-confirmed leptospirosis in Martinique during 2010-2013. Associated factors were hypotension, chest auscultation abnormalities, icterus, oligo/anuria, thrombocytopenia, prothrombin time <68%, high levels of leptospiremia, and infection with L. interrogans serovar Icterohaemorrhagiae/Copenhageni.