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© Pierre Gounon
Entrée de Listeria dans une cellule épithéliale (Grossissement X 10000). Image colorisée.
Publication : Cell

Bacterial adhesion and entry into host cells

Team: Bacteria-Cell Interactions
Member: Pascale Cossart
Member: Javier Pizarro-Cerda
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Cell - 24 Feb 2006

Pizarro-Cerdá J, Cossart P

Link to Pubmed [PMID] – 16497583

Cell 2006 Feb;124(4):715-27

Successful establishment of infection by bacterial pathogens requires adhesion to host cells, colonization of tissues, and in certain cases, cellular invasion-followed by intracellular multiplication, dissemination to other tissues, or persistence. Bacteria use monomeric adhesins/invasins or highly sophisticated macromolecular machines such as type III secretion systems and retractile type IV pili to establish a complex host/pathogen molecular crosstalk that leads to subversion of cellular functions and establishment of disease.