Timeline
![](https://research.pasteur.fr/wp-content/uploads/2015/07/research.pasteur.fr_fig35-150x150.jpg)
Hiroshi Sakamoto
Permanent Researcher
28 Jul 2015
28 Jul 2015
11 May 2015
29 Jun 2014
publication
Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria
Read more19 Dec 2011
publication
Clag9 is not essential for PfEMP1 surface expression in non-cytoadherent Plasmodium falciparum parasites with a chromosome 9 deletion
Read more13 Dec 2011
publication
PfAlbas constitute a new eukaryotic DNA/RNA-binding protein family in malaria parasites
Read more10 Nov 2005
publication
Towards systematic identification of Plasmodium essential genes by transposon shuttle mutagenesis
Read more01 Oct 2004
publication
Conditional mutagenesis using site-specific recombination in Plasmodium berghei
Read more01 Jul 2004
publication
Structure-function relationships of UMP kinases from pyrH mutants of Gram-negative bacteria
Read more01 Feb 2004
publication
Insight into the activation mechanism of Bordetella pertussis adenylate cyclase by calmodulin using fluorescence spectroscopy
Read more01 Jan 2004
publication
Identification and immunochemical location of UMP kinase from Bacillus subtilis
Read more31 May 2002
publication
Comparative modelling and immunochemical reactivity of Escherichia coli UMP kinase
Read more20 Nov 2001
publication
Solution structure and backbone dynamics of the defunct domain of calcium vector protein
Read more01 Apr 2001
publication
Folding units in calcium vector protein of amphioxus: Structural and functional properties of its amino- and carboxy-terminal halves
Read more01 Apr 2001
publication
Mass spectrometric analysis of recombinant adenylate cyclase toxin from Bordetella pertussis strain 18323/pHSP9
Read more11 Jul 2000
publication
Sequential calcium binding to the regulatory domain of calcium vector protein reveals functional asymmetry and a novel mode of structural rearrangement
Read more01 Jul 1999
publication
Assay of nucleoside 2-deoxyribosyltransferase activity with pyruvate kinase/lactate dehydrogenase coupling system
Read more01 Feb 1999
15 Dec 1998
publication
Structures of escherichia coli CMP kinase alone and in complex with CDP: a new fold of the nucleoside monophosphate binding domain and insights into cytosine nucleotide specificity
Read more01 Nov 1998
publication
1H and 15N resonance assignment of the calcium-bound form of the Nereis diversicolor sarcoplasmic Ca(2+)-binding protein
Read more01 Aug 1998
publication
Substitution of an alanine residue for glycine 146 in TMP kinase from Escherichia coli is responsible for bacterial hypersensitivity to bromodeoxyuridine
Read more01 Apr 1997
publication
Structural and catalytic properties of CMP kinase from Bacillus subtilis: a comparative analysis with the homologous enzyme from Escherichia coli
Read more01 Feb 1996
publication
CMP kinase from Escherichia coli is structurally related to other nucleoside monophosphate kinases
Read more18 Apr 1995
publication
Escherichia coli UMP-kinase, a member of the aspartokinase family, is a hexamer regulated by guanine nucleotides and UTP
Read more10 Feb 1995
publication
Enzymatic synthesis of guanine nucleotides labeled with 15N at the 2-amino group of the purine ring
Read more01 Jul 1992
publication
Bordetella pertussis adenylate cyclase toxin. Structural and functional independence of the catalytic and hemolytic activities
Read more01 Mar 1992
publication
Both adenylate cyclase and hemolytic activities are required by Bordetella pertussis to initiate infection
Read more31 Jul 1991
publication
High-level synthesis of active adenylate cyclase toxin of Bordetella pertussis in a reconstructed Escherichia coli system
Read more01 Oct 1990
publication
Deletions affecting hemolytic and toxin activities of Bordetella pertussis adenylate cyclase
Read more01 Aug 1990
01 May 1990
publication
Synthesis and secretion of Bordetella pertussis adenylate cyclase as a 200-kilodalton protein
Read more01 Jun 1989
publication
Comparison of enzyme-linked immunosorbent assay (ELISA) with dot hybridization using 32P- or 2-acetylaminofluorene (AAF)-labelled cDNA probes for the detection and characterization of beet necrotic yellow vein virus
Read more01 Mar 1989
publication
Calibration of target amounts of DNA in hybridization experiments using monoclonal anti-nucleoside antibodies
Read more01 Dec 1988
publication
Secretion of cyclolysin, the calmodulin-sensitive adenylate cyclase-haemolysin bifunctional protein of Bordetella pertussis
Read more01 Dec 1988
publication
Non-radioactive gene probes for the detection of tetracycline and/or minocycline resistance in staphylococci
Read more01 Mar 1987
publication
5-Bromodeoxyuridine in vivo labelling of M13 DNA, and its use as a non-radioactive probe for hybridization experiments
Read more01 Jul 1984