Timeline

Hiroshi Sakamoto
Permanent Researcher
28 Jul 2015
project

Cyanobacterial bioactive compounds

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28 Jul 2015
team

Collection of Cyanobacteria

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11 May 2015
team

Biology of Host-parasite Interactions

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29 Jun 2014
publication

Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria

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19 Dec 2011
publication

Clag9 is not essential for PfEMP1 surface expression in non-cytoadherent Plasmodium falciparum parasites with a chromosome 9 deletion

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13 Dec 2011
publication

PfAlbas constitute a new eukaryotic DNA/RNA-binding protein family in malaria parasites

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10 Nov 2005
publication

Towards systematic identification of Plasmodium essential genes by transposon shuttle mutagenesis

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01 Oct 2004
publication

Conditional mutagenesis using site-specific recombination in Plasmodium berghei

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01 Jul 2004
publication

Structure-function relationships of UMP kinases from pyrH mutants of Gram-negative bacteria

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01 Feb 2004
publication

Insight into the activation mechanism of Bordetella pertussis adenylate cyclase by calmodulin using fluorescence spectroscopy

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01 Jan 2004
publication

Identification and immunochemical location of UMP kinase from Bacillus subtilis

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31 May 2002
publication

Comparative modelling and immunochemical reactivity of Escherichia coli UMP kinase

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20 Nov 2001
publication

Solution structure and backbone dynamics of the defunct domain of calcium vector protein

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01 Apr 2001
publication

Folding units in calcium vector protein of amphioxus: Structural and functional properties of its amino- and carboxy-terminal halves

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01 Apr 2001
publication

Mass spectrometric analysis of recombinant adenylate cyclase toxin from Bordetella pertussis strain 18323/pHSP9

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11 Jul 2000
publication

Sequential calcium binding to the regulatory domain of calcium vector protein reveals functional asymmetry and a novel mode of structural rearrangement

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01 Jul 1999
publication

Assay of nucleoside 2-deoxyribosyltransferase activity with pyruvate kinase/lactate dehydrogenase coupling system

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01 Feb 1999
publication

Immunochemical analysis of UMP kinase from Escherichia coli

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15 Dec 1998
publication

Structures of escherichia coli CMP kinase alone and in complex with CDP: a new fold of the nucleoside monophosphate binding domain and insights into cytosine nucleotide specificity

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01 Nov 1998
publication

1H and 15N resonance assignment of the calcium-bound form of the Nereis diversicolor sarcoplasmic Ca(2+)-binding protein

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01 Aug 1998
publication

Substitution of an alanine residue for glycine 146 in TMP kinase from Escherichia coli is responsible for bacterial hypersensitivity to bromodeoxyuridine

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01 Apr 1997
publication

Structural and catalytic properties of CMP kinase from Bacillus subtilis: a comparative analysis with the homologous enzyme from Escherichia coli

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01 Feb 1996
publication

CMP kinase from Escherichia coli is structurally related to other nucleoside monophosphate kinases

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18 Apr 1995
publication

Escherichia coli UMP-kinase, a member of the aspartokinase family, is a hexamer regulated by guanine nucleotides and UTP

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10 Feb 1995
publication

Enzymatic synthesis of guanine nucleotides labeled with 15N at the 2-amino group of the purine ring

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01 Jul 1992
publication

Bordetella pertussis adenylate cyclase toxin. Structural and functional independence of the catalytic and hemolytic activities

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01 Mar 1992
publication

Both adenylate cyclase and hemolytic activities are required by Bordetella pertussis to initiate infection

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31 Jul 1991
publication

High-level synthesis of active adenylate cyclase toxin of Bordetella pertussis in a reconstructed Escherichia coli system

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01 Oct 1990
publication

Deletions affecting hemolytic and toxin activities of Bordetella pertussis adenylate cyclase

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01 Aug 1990
publication

Gene heterogeneity for tetracycline resistance in Staphylococcus spp

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01 May 1990
publication

Synthesis and secretion of Bordetella pertussis adenylate cyclase as a 200-kilodalton protein

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01 Jun 1989
publication

Comparison of enzyme-linked immunosorbent assay (ELISA) with dot hybridization using 32P- or 2-acetylaminofluorene (AAF)-labelled cDNA probes for the detection and characterization of beet necrotic yellow vein virus

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01 Mar 1989
publication

Calibration of target amounts of DNA in hybridization experiments using monoclonal anti-nucleoside antibodies

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01 Dec 1988
publication

Non-radioactive gene probes for the detection of tetracycline and/or minocycline resistance in staphylococci

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01 Dec 1988
publication

Secretion of cyclolysin, the calmodulin-sensitive adenylate cyclase-haemolysin bifunctional protein of Bordetella pertussis

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01 Mar 1987
publication

5-Bromodeoxyuridine in vivo labelling of M13 DNA, and its use as a non-radioactive probe for hybridization experiments

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01 Jul 1984
publication

Cloning of the iron superoxide dismutase gene (sodB) in Escherichia coli K-12

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