Timeline

Christel Brou

Group Leader

09 Sep 2024

publication

Proteomic landscape of tunneling nanotubes reveals CD9 and CD81 tetraspanins as key regulators

15 Jan 2021

publication

Patient-derived glioblastoma stem cells transfer mitochondria through tunneling nanotubes in tumor organoids.

12 Nov 2020

publication

Fate and propagation of endogenously formed Tau aggregates in neuronal cells.

01 Oct 2020

publication

Tunneling Nanotubes: The Fuel of Tumor Progression?

17 Nov 2018

project

Role of TNTs in tumor networking, heterogeneity, and resistance to therapy.

11 May 2015

team

Membrane Traffic and Pathogenesis

01 Apr 2014

publication

Α-arrestins – new players in Notch and GPCR signaling pathways in mammals

01 Jan 2014

publication

Tracking trafficking of Notch and its ligands in mammalian cells

25 Jul 2013

publication

Α-arrestin 1 (ARRDC1) and β-arrestins cooperate to mediate Notch degradation in mammals

09 Jul 2012

publication

The ubiquitin-specific protease 12 (USP12) is a negative regulator of notch signaling acting on notch receptor trafficking toward degradation

23 Nov 2010

publication

The translation initiation factor 3f (eIF3f) exhibits a deubiquitinase activity regulating Notch activation

25 Sep 2008

publication

Intracellular trafficking of Notch receptors and ligands

16 Jul 2008

publication

AIP4/Itch regulates Notch receptor degradation in the absence of ligand

06 Oct 2006

publication

Itch/AIP4 mediates Deltex degradation through the formation of K29-linked polyubiquitin chains

15 Jun 2005

publication

Generation and characterization of mutant cell lines defective in gamma-secretase processing of Notch and amyloid precursor protein

14 Oct 2004

publication

The notch ligand Delta1 recruits Dlg1 at cell-cell contacts and regulates cell migration

01 Jul 2004

publication

Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor

06 Jun 2003

publication

A little guide for advanced search:

Timeline

Proteomic landscape of tunneling nanotubes reveals CD9 and CD81 tetraspanins as key regulators

Patient-derived glioblastoma stem cells transfer mitochondria through tunneling nanotubes in tumor organoids.

Fate and propagation of endogenously formed Tau aggregates in neuronal cells.

Tunneling Nanotubes: The Fuel of Tumor Progression?

Role of TNTs in tumor networking, heterogeneity, and resistance to therapy.

Membrane Traffic and Pathogenesis

Α-arrestins – new players in Notch and GPCR signaling pathways in mammals

Tracking trafficking of Notch and its ligands in mammalian cells

Α-arrestin 1 (ARRDC1) and β-arrestins cooperate to mediate Notch degradation in mammals

The ubiquitin-specific protease 12 (USP12) is a negative regulator of notch signaling acting on notch receptor trafficking toward degradation

The translation initiation factor 3f (eIF3f) exhibits a deubiquitinase activity regulating Notch activation

Intracellular trafficking of Notch receptors and ligands

AIP4/Itch regulates Notch receptor degradation in the absence of ligand

Itch/AIP4 mediates Deltex degradation through the formation of K29-linked polyubiquitin chains

Generation and characterization of mutant cell lines defective in gamma-secretase processing of Notch and amyloid precursor protein

The notch ligand Delta1 recruits Dlg1 at cell-cell contacts and regulates cell migration

Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor

The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase