Timeline
Xavier Montagutelli
Head of Structure
19 Jul 2024
publication
Broad sarbecovirus neutralization by combined memory B cell antibodies to ancestral SARS-CoV-2.
Read more09 Oct 2023
event
Genomes and Genetics department seminar: Clare Smith (Duke University, Durham, USA); Thursday 18 April @11:00am ; Auditorium François Jacob
Read more21 Sep 2023
publication
Susceptibility to Zika virus in a Collaborative Cross mouse strain is induced by Irf3 deficiency in vitro but requires other variants in vivo.
Read more23 Jun 2023
project
INTRANZIGEANT: Integrated study of Zika virus transmission to identify genetic mechanisms and new antiviral targets
Read more05 Apr 2023
publication
SARS‐CoV‐2‐related bat virus behavior in human‐relevant models sheds light on the origin of COVID‐19
Read more20 Dec 2022
publication
Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response.
Read more08 Nov 2022
publication
Intranasal Exposure to Rift Valley Fever Virus Live-Attenuated Strains Leads to High Mortality Rate in Immunocompetent Mice.
Read more04 Nov 2022
publication
stuart: an R package for the curation of SNP genotypes from experimental crosses.
Read more13 Oct 2022
publication
SARS-CoV-2 infection in domestic rats after transmission from their infected owner
Read more01 Sep 2022
04 Jul 2022
publication
Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.
Read more17 Jun 2022
news
New publication – Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2
Read more04 Apr 2022
publication
Rapid characterization of a Delta-Omicron SARS-CoV-2 recombinant detected in Europe
Read more07 Mar 2022
01 Jan 2022
publication
A mRNA Vaccine Encoding for a RBD 60-mer Nanoparticle Elicits Neutralizing Antibodies and Protective Immunity Against the SARS-CoV-2 Delta Variant in Transgenic K18-hACE2 Mice.
Read more01 Dec 2021
publication
A live measles-vectored COVID-19 vaccine induces strong immunity and protection from SARS-CoV-2 challenge in mice and hamsters.
Read more29 Sep 2021
10 Jul 2021
18 Mar 2021
publication
Variants with the N501Y mutation extend SARS-CoV-2 host range to mice, with contact transmission
Read more09 Mar 2021
publication
Host genetic control of natural killer cell diversity revealed in the Collaborative Cross.
Read more10 Feb 2021
publication
Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains.
Read more01 Feb 2021
publication
The ring finger protein 213 gene (Rnf213) contributes to Rift Valley fever resistance in mice.
Read more01 Dec 2020
publication
Host genetic susceptibility to viral infections: the role of type I interferon induction.
Read more20 Nov 2020
publication
Enhanced Zika virus susceptibility of globally invasive Aedes aegypti populations.
Read more04 Sep 2020
04 Sep 2020
04 Sep 2020
03 Sep 2020
20 Aug 2020
01 Jul 2020
publication
NSs amyloid formation is associated with the virulence of Rift Valley fever virus in mice.
Read more26 May 2020
publication
Genetic dissection of Rift Valley fever pathogenesis: Rvfs2 locus on mouse chromosome 11 enables survival to early-onset hepatitis.
Read more01 Apr 2020
17 Jan 2020
publication
Genetic Diversity of Collaborative Cross Mice Controls Viral Replication, Clinical Severity, and Brain Pathology Induced by Zika Virus Infection, Independently of Oas1b.
Read more17 Dec 2019
publication
A Loss-of-Function Mutation in the Integrin Alpha L (Itgal) Gene Contributes to Susceptibility to Salmonella enterica Serovar Typhimurium Infection in Collaborative Cross Strain CC042.
Read more12 Jul 2019
publication
IFITM proteins inhibit placental syncytiotrophoblast formation and promote fetal demise.
Read more01 Aug 2018
01 Aug 2018
27 Apr 2018
publication
Identification of new loci involved in the host susceptibility to Salmonella Typhimurium in collaborative cross mice
Read more15 Sep 2017
publication
Enhanced Macrophage M1 Polarization and Resistance to Apoptosis Enable Resistance to Plague
Read more29 May 2017
01 Oct 2016
publication
Association of FOXD1 variants with adverse pregnancy outcomes in mice and humans
Read more07 Jun 2016
event
Seminaire conjoint du departement d’immunologie et departement de biologie du développement & cellules souches
Read more14 May 2016
publication
B cells promote tumor progression in a mouse model of HPV-mediated cervical cancer
Read more19 Nov 2015
01 Nov 2015
17 Sep 2015
08 Sep 2015
07 Jul 2015
08 Jan 2015
publication
The genetic basis for susceptibility to Rift Valley fever disease in MBT/Pas mice
Read more01 Jan 2015
02 Dec 2013
publication
Polymorphisms of human placental alkaline phosphatase are associated with in vitro fertilization success and recurrent pregnancy loss
Read more01 May 2013
15 Nov 2012
publication
Resistance to plague of Mus spretus SEG/Pas mice requires the combined action of at least four genetic factors
Read more01 Oct 2012
publication
Exploration of the genetic organization of morphological modularity on the mouse mandible using a set of interspecific recombinant congenic strains between C57BL/6 and mice of the Mus spretus species
Read more16 Aug 2012
publication
Refined mapping of a quantitative trait locus on chromosome 1 responsible for mouse embryonic death
Read more25 May 2012
publication
Nasal bone shape is under complex epistatic genetic control in mouse interspecific recombinant congenic strains
Read more27 Jan 2012
06 Dec 2011
publication
Tissue tropism and target cells of NSs-deleted rift valley fever virus in live immunodeficient mice
Read more16 Nov 2011
publication
Early systemic bacterial dissemination and a rapid innate immune response characterize genetic resistance to plague of SEG mice
Read more16 Nov 2011
publication
Fidgetin-like1 is a strong candidate for a dynamic impairment of male meiosis leading to reduced testis weight in mice
Read more14 Jul 2011
publication
Protoporphyrin retention in hepatocytes and Kupffer cells prevents sclerosing cholangitis in erythropoietic protoporphyria mouse model
Read more17 Jun 2011
publication
Transgenic expression of full-length 2′,5′-oligoadenylate synthetase 1b confers to BALB/c mice resistance against West Nile virus-induced encephalitis
Read more23 Dec 2010
11 Oct 2010
publication
A new mouse model reveals a critical role for host innate immunity in resistance to Rift Valley fever
Read more23 Sep 2010
publication
The stromal gene encoding the CD274 antigen as a genetic modifier controlling survival of mice with γ-radiation-induced T-cell lymphoblastic lymphomas.
Read more23 Sep 2010
publication
Mus spretus SEG/Pas mice resist virulent Yersinia pestis, under multigenic control
Read more01 Feb 2010
publication
Interspecific resources: a major tool for quantitative trait locus cloning and speciation research.
Read more28 May 2009
publication
Genetic analysis of skull shape variation and morphological integration in the mouse using interspecific recombinant congenic strains between C57BL/6 and mice of the mus spretus species
Read more01 May 2009
15 Mar 2009
publication
A role for stroma-derived annexin A1 as mediator in the control of genetic susceptibility to T-cell lymphoblastic malignancies through prostaglandin E2 secretion.
Read more01 Jan 2009
publication
Identification of Quantitative Trait Loci responsible for embryonic lethality in mice assessed by ultrasonography.
Read more01 Aug 2008
publication
Maternal environment interacts with modifier genes to influence progression of nephrotic syndrome.
Read more01 Jan 2008
publication
Gene expression regulation in the context of mouse interspecific mosaic genomes.
Read more01 Jul 2007
publication
Centimorgan-range one-step mapping of fertility traits using interspecific recombinant congenic mice.
Read more01 Jul 2007
01 Jun 2007
publication
Lymphocytic choriomeningitis infection undetected by dirty-bedding sentinel monitoring and revealed after embryo transfer of an inbred strain derived from wild mice
Read more15 Jan 2007
publication
Increased plasma transferrin, altered body iron distribution, and microcytic hypochromic anemia in ferrochelatase-deficient mice.
Read more01 Jan 2006
publication
Ursodesoxycholic acid and heme-arginate are unable to improve hematopoiesis and liver injury in an erythropoietic protoporphyria mouse model.
Read more27 Jan 2005
publication
A mouse model provides evidence that genetic background modulates anemia and liver injury in erythropoietic protoporphyria
Read more01 Jan 2005
publication
Increased mitochondrial respiratory chain enzyme activities correlate with minor extent of liver damage in mice suffering from erythropoietic protoporphyria.
Read more01 Nov 2004
publication
The Collaborative Cross, a community resource for the genetic analysis of complex traits.
Read more01 Oct 2004
publication
Simple duplex fecal PCR assay that allows identification of false-negative results in Helicobacter sp.-infected mice
Read more01 Oct 2004
24 Jan 2004
01 Nov 2003
publication
Structural and functional genomics and evolutionary relationships in the cluster of genes encoding murine 2′,5′-oligoadenylate synthetases
Read more01 Jun 2003
publication
Infection of mouse neurones by West Nile virus is modulated by the interferon-inducible 2′-5′ oligoadenylate synthetase 1b protein
Read more18 Apr 2003
publication
Desmoglein 4 in hair follicle differentiation and epidermal adhesion: evidence from inherited hypotrichosis and acquired pemphigus vulgaris.
Read more01 Jan 2003
01 Dec 2002
publication
Loss of cell adhesion in Dsg3bal-Pas mice with homozygous deletion mutation (2079del14) in the desmoglein 3 gene.
Read more19 Aug 2002
publication
A nonsense mutation in the gene encoding 2′-5′-oligoadenylate synthetase/L1 isoform is associated with West Nile virus susceptibility in laboratory mice
Read more05 Apr 2002
publication
The Ig light chain restricted B6.kappa(-)lambda(SEG) mouse strain suggests that the IGL locus genomic organization is subject to constant evolution
Read more01 Nov 2000
01 Jul 2000
publication
Reversion of hepatobiliary alterations By bone marrow transplantation in a murine model of erythropoietic protoporphyria.
Read more01 Jun 2000
01 Jan 1999
publication
Identification of the mutation in the alkaptonuria mouse model. Mutations in brief no. 216. Online.
Read more01 Jan 1999
01 Dec 1998
01 Dec 1998
publication
Linkage of a major quantitative trait locus to Yaa gene-induced lupus-like nephritis in (NZW x C57BL/6)F1 mice.
Read more01 Jul 1998
publication
Maintenance of granulocyte numbers during acute peritonitis is defective in galectin-3-null mutant mice.
Read more01 May 1998
01 Sep 1997
publication
Vesicle formation and follicular root sheath separation in mice homozygous for deleterious alleles at the balding (bal) locus.
Read more15 Jan 1997
01 Aug 1996
publication
Epistatic control of non-Mendelian inheritance in mouse interspecific crosses.
Read more01 Aug 1996
publication
Male sterility caused by sperm cell-specific structural abnormalities in ebouriffé, a new mutation of the house mouse.
Read more01 Jul 1996
publication
Lanceolate hair (lah): a recessive mouse mutation with alopecia and abnormal hair.
Read more01 May 1995
01 Apr 1995
publication
Tissue- and developmental stage-specific imprinting of the mouse proinsulin gene, Ins2.
Read more01 Oct 1994
publication
A high-resolution genetic map of mouse chromosome 5 encompassing the reeler (rl) locus.
Read more01 Jul 1994
01 Jun 1994
publication
Genetic reassignment of the insulin-1 (Ins1) gene to distal mouse chromosome 19.
Read more01 Jan 1994
publication
Homogentisic acid oxidase activity in homozygous and heterozygous alkaptonuric mice.
Read more01 Jan 1994
01 Jan 1994
publication
aku, a mutation of the mouse homologous to human alkaptonuria, maps to chromosome 16.
Read more01 Sep 1993
publication
Mapping loci influencing the persistence of Theiler’s virus in the murine central nervous system.
Read more01 Jun 1993
01 Jan 1993
publication
Re-localization of Actsk-1 to mouse chromosome 8, a new region of homology with human chromosome 1.
Read more01 Jan 1993
publication
DNA segments mapped by reciprocal use of microsatellite primers between mouse and rat.
Read more01 Aug 1992
publication
The interaction of two groups of murine genes determines the persistence of Theiler’s virus in the central nervous system.
Read more01 Feb 1992
01 Jan 1992
publication
Polymorphisms revealed by PCR with single, short-sized, arbitrary primers are reliable markers for mouse and rat gene mapping.
Read more01 Jan 1992
01 Nov 1991
publication
Erythropoietic protoporphyria in the house mouse. A recessive inherited ferrochelatase deficiency with anemia, photosensitivity, and liver disease.
Read more01 May 1991
publication
Recent evolutionary origin of the expression of the glial fibrillary acidic protein (GFAP) in lens epithelial cells. A molecular and genetic analysis of various mouse species.
Read more01 Jan 1991
publication
Two-dimensional gel analysis of complex DNA families: methodology and apparatus.
Read more01 Jan 1991
publication
PCR-analyzed microsatellites: data concerning laboratory and wild-derived mouse inbred strains.
Read more01 Nov 1990