Ligne de temps
21 févr. 2019
17 janv. 2018
publication
A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies
Lire plus27 sept. 2017
05 déc. 2016
publication
The Shh Topological Domain Facilitates the Action of Remote Enhancers by Reducing the Effects of Genomic Distances
Lire plus05 oct. 2016
publication
Formation of new chromatin domains determines pathogenicity of genomic duplications
Lire plus27 juin 2016
publication
Gene regulation at a distance: from remote enhancers to 3D regulatory ensembles
Lire plus11 avr. 2016
publication
Cis-regulatory architecture of a brain signaling center predates the origin of chordates
Lire plus12 nov. 2015
publication
Gene regulation during development in the light of topologically associating domains
Lire plus22 mai 2015
publication
Model mice for 15q11-13 duplication syndrome exhibit late-onset obesity and altered lipid metabolism
Lire plus29 janv. 2015
publication
Hoxa2 selectively enhances Meis binding to change a branchial arch ground state
Lire plus08 janv. 2015
publication
A discrete transition zone organizes the topological and regulatory autonomy of the adjacent tfap2c and bmp7 genes
Lire plus05 juin 2014
publication
The architecture of gene expression: integrating dispersed cis-regulatory modules into coherent regulatory domains
Lire plus25 mai 2014
publication
Long-range enhancers regulating Myc expression are required for normal facial morphogenesis
Lire plus07 janv. 2014
18 sept. 2013
publication
Efficient site-specific transgenesis and enhancer activity tests in medaka using PhiC31 integrase
Lire plus01 juin 2013
publication
A switch between topological domains underlies HoxD genes collinearity in mouse limbs
Lire plus06 mai 2013
publication
From remote enhancers to gene regulation: charting the genome’s regulatory landscapes
Lire plus02 avr. 2013
28 févr. 2013
publication
An integrated holo-enhancer unit defines tissue and gene specificity of the Fgf8 regulatory landscape
Lire plus01 févr. 2013
publication
Phenotypic impact of genomic structural variation: insights from and for human disease
Lire plus07 août 2012
23 nov. 2011
20 mars 2011
publication
Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor
Lire plus29 déc. 2010
publication
A systematic enhancer screen using lentivector transgenesis identifies conserved and non-conserved functional elements at the Olig1 and Olig2 locus
Lire plus14 janv. 2010
01 janv. 2010
publication
Control of vertebrate Hox clusters by remote and global cis-acting regulatory sequences
Lire plus06 mars 2009
16 déc. 2008
publication
Analysis of mammalian gene batteries reveals both stable ancestral cores and highly dynamic regulatory sequences
Lire plus07 mai 2008
05 avr. 2008
publication
Characterization of mouse Dactylaplasia mutations: a model for human ectrodactyly SHFM3
Lire plus01 janv. 2008
publication
Global control regions and regulatory landscapes in vertebrate development and evolution
Lire plus23 mars 2007
03 juil. 2005
publication
Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes
Lire plus01 juil. 2004
publication
Six1 and Eya1 expression can reprogram adult muscle from the slow-twitch phenotype into the fast-twitch phenotype
Lire plus15 juin 2004
publication
Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression
Lire plus01 mai 2003
publication
A global control region defines a chromosomal regulatory landscape containing the HoxD cluster
Lire plus01 oct. 2002
publication
Fiber-type specific and position-dependent expression of a transgene in limb muscles
Lire plus01 avr. 2002
publication
A t(2;8) balanced translocation with breakpoints near the human HOXD complex causes mesomelic dysplasia and vertebral defects
Lire plus01 sept. 2001
publication
Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations
Lire plus13 oct. 2000
publication
The alpha subunits of Gz and Gi interact with the eyes absent transcription cofactor Eya2, preventing its interaction with the six class of homeodomain-containing proteins
Lire plus18 juin 1999
publication
Developmental regulation of the aldolase A muscle-specific promoter during in vivo muscle maturation is controlled by a nuclear receptor binding element
Lire plus24 nov. 1998
publication
Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site
Lire plus12 juin 1998
publication
Proximal sequences of the aldolase A fast muscle-specific promoter direct nerve- and activity-dependent expression in transgenic mice
Lire plus01 mars 1998
publication
The human pH aldolase A promoter directs widespread but muscle-predominant expression in transgenic mice
Lire plus01 janv. 1998
publication
A binding site for nuclear receptors is required for the differential expression of the aldolase A fast-twitch muscle promoter in body and head muscles
Lire plus01 févr. 1997
publication
A combination of MEF3 and NFI proteins activates transcription in a subset of fast-twitch muscles
Lire plus13 oct. 1995
publication