Ligne de temps

Florian Muller
Chef(fe) de Groupe
06 juil. 2024
publication

A point cloud segmentation framework for image-based spatial transcriptomics.

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10 avr. 2024
software

Comseg – Cell segmentation for spatial transcriptomics data

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13 févr. 2024
publication

pyHiM: a new open-source, multi-platform software package for spatial genomics based on multiplexed DNA-FISH imaging.

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30 juin 2023
tool

smiFISH : a cheap and versatile smFISH approach

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30 juin 2023
project

autoFISH : a modular toolbox for sequential FISH experiments

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30 juin 2023
software

FISH-quant v2: a scalable and modular tool for smFISH image analysis

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27 juin 2023
team

Imagerie quantitative de l’ARN

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28 avr. 2023
publication

An interactive murine single-cell atlas of the lung responses to radiation injury.

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08 mars 2023
publication

A specific molecular signature in SARS-CoV-2-infected kidney biopsies.

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14 févr. 2023
publication

PointFISH: Learning Point Cloud Representations for RNA Localization Patterns

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01 janv. 2023
publication

Excessive self-grooming, gene dysregulation and imbalance between the striosome and matrix compartments in the striatum of Shank3 mutant mice.

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24 oct. 2022
publication

HT-smFISH: a cost-effective and flexible workflow for high-throughput single-molecule RNA imaging.

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01 juin 2022
publication

FISH-quant v2: a scalable and modular tool for smFISH image analysis.

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01 avr. 2022
publication

Sensitive visualization of SARS-CoV-2 RNA with CoronaFISH.

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24 janv. 2022
publication

piRNAs initiate transcriptional silencing of spermatogenic genes during C. elegans germline development.

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01 déc. 2021
publication

The kinesin KIF1C transports APC-dependent mRNAs to cell protrusions.

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01 août 2021
publication

Live single-cell transcriptional dynamics via RNA labelling during the phosphate response in plants.

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23 juil. 2021
publication

Stochastic pausing at latent HIV-1 promoters generates transcriptional bursting.

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08 avr. 2021
publication

Spatial transcriptomics for respiratory research and medicine.

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04 mars 2021
publication

Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos.

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01 mars 2021
publication

A choreography of centrosomal mRNAs reveals a conserved localization mechanism involving active polysome transport.

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04 janv. 2021
publication

Clustering and reverse transcription of HIV-1 genomes in nuclear niches of macrophages.

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19 nov. 2020
publication

Functional compensation precedes recovery of tissue mass following acute liver injury.

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28 sept. 2020
publication

A Dual Protein-mRNA Localization Screen Reveals Compartmentalized Translation and Widespread Co-translational RNA Targeting.

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15 juin 2020
publication

mRNA localization is linked to translation regulation in the Caenorhabditis elegans germ lineage.

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18 mai 2020
publication

Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes.

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01 déc. 2019
publication

ImJoy: an open-source computational platform for the deep learning era

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11 juil. 2019
publication

A Deep Learning Approach To Identify MRNA Localization Patterns

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15 avr. 2019
publication

Co-translational assembly of mammalian nuclear multisubunit complexes

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07 mars 2019
publication

The molecular logic of Nanog-induced self-renewal in mouse embryonic stem cells

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01 déc. 2018
publication

A computational framework to study sub-cellular RNA localization

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02 août 2018
publication

A Growing Toolbox to Image Gene Expression in Single Cells: Sensitive Approaches for Demanding Challenges

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29 mai 2018
publication

Visualization of Arenavirus RNA Species in Individual Cells by Single-Molecule Fluorescence Hybridization Suggests a Model of Cyclical Infection and Clearance during Persistence

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17 août 2017
team

BioImagerie Photonique (UTechS PBI)

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10 oct. 2016
publication

Mitotic binding of Esrrb marks key regulatory regions of the pluripotency network

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05 sept. 2016
publication

Visualization of single endogenous polysomes reveals the dynamics of translation in live human cells

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05 sept. 2016
publication

smiFISH and FISH-quant – a flexible single RNA detection approach with super-resolution capability

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26 août 2016
publication

Single molecule tracking of Ace1p in Saccharomyces cerevisiae defines a characteristic residence time for non-specific interactions of transcription factors with chromatin

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27 juil. 2016
publication

A single-molecule view of transcription reveals convoys of RNA polymerases and multi-scale bursting

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07 avr. 2016
publication

Divergent Binding and Transactivation by Two Related Steroid Receptors at the Same Response Element

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11 sept. 2015
software

FISH-quant: automatically counting transcripts in RNA-FISH images

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18 août 2014
publication

Distinctly different dynamics and kinetics of two steroid receptors at the same response elements in living cells

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26 juin 2014
publication

Transcription factors modulate c-Fos transcriptional bursts

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06 mars 2014
publication

PRC1 components exhibit different binding kinetics in Polycomb bodies

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19 nov. 2013
publication

Stable assembly of HIV-1 export complexes occurs cotranscriptionally

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11 sept. 2013
publication

Quantifying transcription factor kinetics: at work or at play?

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01 août 2013
publication

Convergence of chromatin binding estimates in live cells

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01 juil. 2013
publication

Defective cerebellar control of cortical plasticity in writer’s cramp

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13 juin 2013
publication

Genome-wide measurement of protein-DNA binding dynamics using competition ChIP

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01 avr. 2013
publication

FISH-quant: automatic counting of transcripts in 3D FISH images

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09 déc. 2012
publication

Fast multicolor 3D imaging using aberration-corrected multifocus microscopy

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11 avr. 2012
publication

Genome-wide protein-DNA binding dynamics suggest a molecular clutch for transcription factor function

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03 avr. 2012
publication

Minimizing the impact of photoswitching of fluorescent proteins on FRAP analysis

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01 janv. 2012
publication

Monitoring dynamic binding of chromatin proteins in vivo by fluorescence recovery after photobleaching

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14 nov. 2010
publication

Three-dimensional cellular ultrastructure resolved by X-ray microscopy

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01 nov. 2010
publication

Cross-validating FRAP and FCS to quantify the impact of photobleaching on in vivo binding estimates

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21 avr. 2010
publication

FRAP and kinetic modeling in the analysis of nuclear protein dynamics: what do we really know?

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11 mars 2010
publication

Dissecting the binding mechanism of the linker histone in live cells: an integrated FRAP analysis

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02 sept. 2008
publication

Regulation of TATA-binding protein dynamics in living yeast cells

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07 avr. 2008
publication

Intracellular delivery of acetyl-histone peptides inhibits native bromodomain-chromatin interactions and impairs mitotic progression

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16 janv. 2008
publication

Evidence for a common mode of transcription factor interaction with chromatin as revealed by improved quantitative fluorescence recovery after photobleaching

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05 mai 2006
publication

Analysis of binding at a single spatially localized cluster of binding sites by fluorescence recovery after photobleaching

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