Ligne de temps
Eric Legrand
Ingénieur(e) de Recherche
31 janv. 2024
project
Caractérisation du rôle récepteur cellulaire utilisé par le parasite Plasmodium vivax au cours des formes bénignes mais récurrentes de paludisme : PVINVASION (2023-028).
Lire plus19 déc. 2023
project
Étude des traitements antipaludiques : identification de nouveaux candidats médicaments et notamment des anticorps : BPV (2023-018)
Lire plus28 sept. 2023
publication
Increasing Prevalence of Artemisinin-Resistant HRP2-Negative Malaria in Eritrea
Lire plus19 juil. 2021
publication
Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness.
Lire plus22 juin 2021
publication
Therapeutic efficacy of artesunate-amodiaquine and artemether-lumefantrine and polymorphism in Plasmodium falciparum kelch13-propeller gene in Equatorial Guinea.
Lire plus03 août 2020
publication
Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R561H mutant parasites in Rwanda.
Lire plus24 mai 2020
publication
Molecular assessment of kelch13 non-synonymous mutations in Plasmodium falciparum isolates from Central African Republic (2017-2019).
Lire plus30 mars 2020
publication
WHO malaria nucleic acid amplification test external quality assessment scheme: results of distribution programmes one to three.
Lire plus01 mars 2020
publication
Human Plasmodium vivax diversity, population structure and evolutionary origin.
Lire plus01 nov. 2019
10 avr. 2019
publication
African isolates show a high proportion of multiple copies of the Plasmodium falciparum plasmepsin-2 gene, a piperaquine resistance marker
Lire plus16 mars 2019
29 déc. 2018
20 sept. 2018
publication
Molecular assays for antimalarial drug resistance surveillance: A target product profile
Lire plus24 avr. 2018
publication
A novel field-based molecular assay to detect validated artemisinin-resistant k13 mutants
Lire plus25 janv. 2018
01 déc. 2017
publication
Antiplasmodial activities of dyes against Plasmodium falciparum asexual and sexual stages: Contrasted uptakes of triarylmethanes Brilliant green, Green S (E142), and Patent Blue V (E131) by erythrocytes.
Lire plus01 nov. 2017
publication
Evolutionary structure of Plasmodium falciparum major variant surface antigen genes in South America: Implications for epidemic transmission and surveillance.
Lire plus08 nov. 2016
03 nov. 2016
publication
A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype-genotype association study
Lire plus22 sept. 2016
publication
Evaluation of circumsporozoite protein of Plasmodium vivax to estimate its prevalence in Oiapoque, Amapa state, Brazil, bordering French Guiana.
Lire plus23 juin 2016
01 mai 2016
publication
Malaria Hyperendemicity and Risk for Artemisinin Resistance among Illegal Gold Miners, French Guiana.
Lire plus12 avr. 2016
publication
Plasmodium copy number variation scan: gene copy numbers evaluation in haploid genomes
Lire plus10 nov. 2015
publication
Frequency and distribution of mixed Plasmodium falciparum-vivax infections in French Guiana between 2000 and 2008.
Lire plus09 oct. 2015
publication
Efficacy in the treatment of malaria by Plasmodium vivax in Oiapoque, Brazil, on the border with French Guiana: the importance of control over external factors.
Lire plus02 oct. 2015
news
iGEM Pasteur Team ranked in the Bronze Medal category at the Giant Jamboree in Boston
Lire plus15 sept. 2015
publication
Adaptive evolution of malaria parasites in French Guiana: Reversal of chloroquine resistance by acquisition of a mutation in pfcrt.
Lire plus25 juil. 2015
publication
Absence of correlation between ex vivo susceptibility to doxycycline and pfteQ-pfmdt gene polymorphism in French Guiana.
Lire plus04 juin 2015
publication
Use of Plasmodium falciparum culture-adapted field isolates for in vitro exflagellation-blocking assay.
Lire plus11 mai 2015
11 mai 2015
01 mars 2015
publication
Development of a single nucleotide polymorphism barcode to genotype Plasmodium vivax infections.
Lire plus23 févr. 2015
publication
Heterogeneity among Mycobacterium ulcerans from French Guiana revealed by multilocus variable number tandem repeat analysis (MLVA)
Lire plus19 janv. 2015
publication
COIL: a methodology for evaluating malarial complexity of infection using likelihood from single nucleotide polymorphism data.
Lire plus01 oct. 2014
04 août 2014
publication
Genetic diversity and population structure of Plasmodium vivax isolates from Sudan, Madagascar, French Guiana and Armenia
Lire plus01 août 2014
01 avr. 2014
publication
Patterns of selection on Plasmodium falciparum erythrocyte-binding antigens after the colonization of the New World.
Lire plus01 nov. 2013
publication
Whole genome sequencing of field isolates reveals a common duplication of the Duffy binding protein gene in Malagasy Plasmodium vivax strains.
Lire plus08 juin 2013
publication
Land cover, land use and malaria in the Amazon: a systematic literature review of studies using remotely sensed data.
Lire plus01 janv. 2013
publication
High performance of histidine-rich protein 2 based rapid diagnostic tests in French Guiana are explained by the absence of pfhrp2 gene deletion in P. falciparum.
Lire plus01 avr. 2012
publication
Investigation of a sudden malaria outbreak in the isolated Amazonian village of Saul, French Guiana, January-April 2009.
Lire plus01 mars 2012
publication
Discordant temporal evolution of Pfcrt and Pfmdr1 genotypes and Plasmodium falciparum in vitro drug susceptibility to 4-aminoquinolines after drug policy change in French Guiana.
Lire plus10 janv. 2012
13 mai 2010
publication
Identification of a Mutant PfCRT-Mediated Chloroquine Tolerance Phenotype in Plasmodium falciparum.
Lire plus13 mai 2010
publication
Identification of a mutant PfCRT-mediated chloroquine tolerance phenotype in Plasmodium falciparum
Lire plus01 janv. 2010
publication
Geographic structuring of the Plasmodium falciparum sarco(endo)plasmic reticulum Ca2+ ATPase (PfSERCA) gene diversity.
Lire plus01 juil. 2009
publication
High prevalence and fixation of Plasmodium vivax dhfr/dhps mutations related to sulfadoxine/pyrimethamine resistance in French Guiana.
Lire plus11 mars 2009
publication
Genetic diversity of msp3alpha and msp1_b5 markers of Plasmodium vivax in French Guiana
Lire plus01 sept. 2008
publication
Dihydroethanoanthracene derivatives reverse in vitro quinoline resistance in Plasmodium falciparum malaria
Lire plus17 déc. 2007
publication
Sequence analysis of Plasmodium falciparum cytochrome b in multiple geographic sites
Lire plus25 oct. 2007
publication
Evaluation of the intra- and inter-specific genetic variability of Plasmodium lactate dehydrogenase
Lire plus22 oct. 2007
publication
In vitro monitoring of Plasmodium falciparum drug resistance in French Guiana: a synopsis of continuous assessment from 1994 to 2005
Lire plus16 avr. 2007
publication
First case of emergence of atovaquone resistance in Plasmodium falciparum during second-line atovaquone-proguanil treatment in South America
Lire plus26 avr. 2006
01 déc. 2005
publication
Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6
Lire plus01 août 2005
publication
Countrywide survey shows very high prevalence of Plasmodium falciparum multilocus resistance genotypes in Cambodia
Lire plus21 juin 2005
publication
Molecular analysis of two local falciparum malaria outbreaks on the French Guiana coast confirms the msp1 B-K1/varD genotype association with severe malaria
Lire plus01 déc. 2004
publication
Taxonomic and phylogenetic status of non-tuberculous mycobacteria in a Caribbean setting
Lire plus01 sept. 2004
publication
Plasmodium falciparum malaria in splenectomized patients: two case reports in French Guiana and a literature review
Lire plus01 juil. 2003
publication
Genotyping of the Mycobacterium tuberculosis complex using MIRUs: association with VNTR and spoligotyping for molecular epidemiology and evolutionary genetics
Lire plus01 févr. 2003
publication
Molecular characterization and drug resistance patterns of strains of Mycobacterium tuberculosis isolated from patients in an AIDS counseling center in Port-au-Prince, Haiti: a 1-year study
Lire plus01 juin 2002
publication
A pulsed-field gel electrophoresis study of Mycobacterium fortuitum in a Caribbean setting underlines high genetic diversity of the strains and excludes nosocomial outbreaks
Lire plus01 mai 2002
publication
Molecular characterization of multiple-drug-resistant Mycobacterium tuberculosis isolates from northwestern Russia and analysis of rifampin resistance using RNA/RNA mismatch analysis as compared to the line probe assay and sequencing of the rpoB gene
Lire plus01 déc. 2001
publication
Mycobacterium tuberculosis phylogeny reconstruction based on combined numerical analysis with IS1081, IS6110, VNTR, and DR-based spoligotyping suggests the existence of two new phylogeographical clades
Lire plus01 oct. 2001
publication
Rapid differentiation of “Mycobacterium canettii” from other Mycobacterium tuberculosis complex organisms by PCR-restriction analysis of the hsp65 gene
Lire plus01 avr. 2001
publication
Use of spoligotyping to study the evolution of the direct repeat locus by IS6110 transposition in Mycobacterium tuberculosis
Lire plus01 avr. 2001
01 déc. 2000
publication
Description of a novel Mycobacterium simiae allelic variant isolated from Caribbean AIDS patients by PCR-restriction enzyme analysis and sequencing of hsp65 gene
Lire plus01 déc. 2000
publication
[Recent developments of spoligotyping as applied to the study of epidemiology, biodiversity and molecular phylogeny of the Mycobacterium tuberculosis complex]
Lire plus01 août 2000
publication
A molecular epidemiological study of Mycobacterium simiae isolated from AIDS patients in Guadeloupe
Lire plus01 juil. 2000
publication
[Mycobacterium avium-intracellulare complex: phenotypic and genotypic markers and the molecular basis for interspecies transmission]
Lire plus01 déc. 1999
publication
[Genotypic diversity of Mycobacterium tuberculosis in the Guiana-Antilles region]
Lire plus01 mai 1999
publication
Tuberculosis in the Caribbean: using spacer oligonucleotide typing to understand strain origin and transmission
Lire plus01 janv. 1999
publication
Postantibiotic effects of rifampin, amikacin, clarithromycin and ethambutol used alone or in various two-, three- and four-drug combinations against Mycobacterium avium
Lire plus01 nov. 1997
publication
Postantibiotic effect of amikacin, rifampin, sparfloxacin, clofazimine and clarithromycin against Mycobacterium avium
Lire plus01 déc. 1996
publication